NOX2-IN-2 diTFA
Based on 1 Customer Validation
NOX2-IN-2 diTFA (compound 33) is a potent NOX2 inhibitor targeting the p47phox-p22phox protein-protein interaction with a Ki of 0.24 μM. NOX2-IN-2 diTFA inhibits ROS production derived from NOX2 in cells.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 98.15%
- CAS No.: 2648709-80-0
- 화학식: C29H27F6N7O7
- 분자량:699.56
-
보관:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Chemical Information
-
CAS No. 2648709-80-0
-
Appearance Solid
-
분자량 699.56
-
화학식 C29H27F6N7O7
-
Color White to off-white
-
SMILES
NC1=NC2=CC=C(C=C2C=C1)OCC3=CN(N=N3)CCOCCOC4=CC=C5N=C(C=CC5=C4)N.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
용액&용해도
DMSO : 125 mg/mL (178.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
-
Data Sheet (267 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4295 mL | 7.1473 mL | 14.2947 mL | 35.7367 mL |
| 5 mM | 0.2859 mL | 1.4295 mL | 2.8589 mL | 7.1473 mL | |
| 10 mM | 0.1429 mL | 0.7147 mL | 1.4295 mL | 3.5737 mL | |
| 15 mM | 0.0953 mL | 0.4765 mL | 0.9530 mL | 2.3824 mL | |
| 20 mM | 0.0715 mL | 0.3574 mL | 0.7147 mL | 1.7868 mL | |
| 25 mM | 0.0572 mL | 0.2859 mL | 0.5718 mL | 1.4295 mL | |
| 30 mM | 0.0476 mL | 0.2382 mL | 0.4765 mL | 1.1912 mL | |
| 40 mM | 0.0357 mL | 0.1787 mL | 0.3574 mL | 0.8934 mL | |
| 50 mM | 0.0286 mL | 0.1429 mL | 0.2859 mL | 0.7147 mL | |
| 60 mM | 0.0238 mL | 0.1191 mL | 0.2382 mL | 0.5956 mL | |
| 80 mM | 0.0179 mL | 0.0893 mL | 0.1787 mL | 0.4467 mL | |
| 100 mM | 0.0143 mL | 0.0715 mL | 0.1429 mL | 0.3574 mL |