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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
phosphomannomutase
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "phosphomannomutase" in MCE Product Catalog:
1
1 Cited Publications
Research Areas:
ML089 is an orally active inhibitor of phosphomannose isomerase (PMI) and PHOSPHO1, with an IC50 value of 1.3 μM against human PMI and an IC50 value of 0.8 μM against PHOSPHO1. ML089 blocks the catabolism of mannose-6-phosphate, directs mannose-6-phosphate to participate in protein glycosylation, increases mannose incorporation into cellular proteins, and reduces tritiated water production from mannose-6-phosphate. ML089 inhibits PMI in living cells. ML089 can be used in research related to congenital disorder of glycosylation type Ia (CDG-Ia) .
Cat. No.: HY-N8365
CAS No.: 91183-87-8
Category:
Target:
Cat. No.: HY-113002
CAS No.: 10139-18-1
Target:
Research Areas:
α-D-Glucose 1,6-bisphosphate is an activator of PMM2 and phosphoglucomutase. α-D-Glucose 1,6-bisphosphate regulates glycogen metabolism, glycolysis, amino sugar synthesis, as well as the formation of bacterial cell walls and capsules. α-D-Glucose 1,6-bisphosphate can be used in studies related to pmm2-cdg (cdg-1a or Jaeken syndrome) .
Cat. No.: HY-113002A
CAS No.: 71662-13-0
Target:
α-D-Glucose 1,6-bisphosphate cyclohexanamine is an activator of PMM2 and phosphoglucomutase. α-D-Glucose 1,6-bisphosphate cyclohexanamine regulates glycogen metabolism, glycolysis, amino sugar synthesis, as well as the formation of bacterial cell walls and capsules. α-D-Glucose 1,6-bisphosphate cyclohexanamine can be used in studies related to pmm2-cdg (cdg-1a or Jaeken syndrome) .
Cat. No.: HY-P71021
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PMM2; PMI; Prev. CDG1; Phosphomannose Isomerase 1; CDG1a; PMM 2; PMI1; Congenital Disorder Of Glycosylation, Type Ia; CDGS; phosphomannomutase; phosphomannomutase 2; Mannose-6-Phosphate Isomerase
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
