91183-87-8
Chemical Structure
α-D-Glucose 1,6-bisphosphate tetrapotassium
- CAS No.: 91183-87-8
- Formula:C6H10K4O12P2
- Molecular Weight:492.48
IUPAC Name: potassium ((2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-(phosphonatooxy)tetrahydro-2H-pyran-2-yl)methyl phosphate
InChIKey: OVRXVCAVDXBPQT-QMKHLHGBSA-J
SMILES: O=P(O[K])(O[K])OC[C@H]1O[C@@H]([C@@H]([C@H]([C@@H]1O)O)O)OP(O[K])(O[K])=O
Biological Activity: α-D-Glucose 1,6-bisphosphate tetrapotassium is an activator of PMM2 and phosphoglucomutase. α-D-Glucose 1,6-bisphosphate tetrapotassium regulates glycogen metabolism, glycolysis, amino sugar synthesis, as well as the formation of bacterial cell walls and capsules. α-D-Glucose 1,6-bisphosphate tetrapotassium can be used in studies related to pmm2-cdg (cdg-1a or Jaeken syndrome)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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α-D-Glucose 1,6-bisphosphate tetrapotassium | 98.74% | α-D-Glucose 1,6-bisphosphate tetrapotassium is an activator of PMM2 and phosphoglucomutase. α-D-Glucose 1,6-bisphosphate tetrapotassium regulates glycogen metabolism, glycolysis, amino sugar synthesis, as well as the formation of bacterial cell walls and capsules. α-D-Glucose 1,6-bisphosphate tetrapotassium can be used in studies related to pmm2-cdg (cdg-1a or Jaeken syndrome). | ||||||||||||||||||||
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References
- [1]. Neumann N, et al. Glucose-1,6-Bisphosphate, a Key Metabolic Regulator, Is Synthesized by a Distinct Family of α-Phosphohexomutases Widely Distributed in Prokaryotes. mBio. 2022;13(4):e0146922. [Content Brief]
- [2]. Monticelli M, et al. β-Glucose-1,6-Bisphosphate Stabilizes Pathological Phophomannomutase2 Mutants In Vitro and Represents a Lead Compound to Develop Pharmacological Chaperones for the Most Common Disorder of Glycosylation, PMM2-CDG. Int J Mol Sci. 2019;20(17):4164. Published 2019 Aug 26. [Content Brief]
