5 Results for "

preosteoblast differentiation

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "preosteoblast differentiation" in MCE Product Catalog:

D3-βArr
D3-βArr
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Cat. No.: HY-124867
CAS No.: 662164-09-2
Purity:  99.49%
Target:  

TSH Receptor

Research Areas:  

Endocrinology

D3-βArr is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 by direct TSHR activation and potentiates TSH-mediated preosteoblast differentiation in vitro .
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Paeonolide
Paeonolide
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Cat. No.: HY-N2156
CAS No.: 72520-92-4
Category:  

Ketones, Aldehydes, Acids Plants Paeoniaceae Disease Research Fields Inflammation/Immunology Paeonia suffruticosa Andr.

Target:  

ERK TGF-beta/Smad Wnt β-catenin JNK p38 MAPK

Paeonolide, found in Paeonia suffruticosa, is an ERK1/2 activator. Paeonolide promotes early and late osteoblast differentiation, stimulates pre-osteoblast transmigration, and activates the BMP-Smad1/5/8, Wnt-β-catenin, JNK and p38 pathways. Paeonolide can be used for the research of osteoporosis, periodontitis .
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Nodakenetin
Nodakenetin
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Cat. No.: HY-N2276
CAS No.: 495-32-9
Category:  

Chrysanthemum × morifolium (Ramat.) Hemsl. Coumarins Phenylpropanoids Plants Umbelliferae Disease Research Fields Inflammation/Immunology

Target:  

Wnt β-catenin c-Myc Survivin

Nodakenetin is an orally active Wnt/β-catenin pathway activator. Nodakenetin reduces the level of DKK1, and upregulates c-Myc, cyclin D1 and survivin . Nodakenetin induces osteoprogenitor cell differentiation, upregulates bone formation biomarkers and prevents bone microstructure degeneration. Nodakenetin induces irritant skin reactions. Nodakenetin improves bone microstructure and histomorphometric parameters in osteoporotic mouse models. Nodakenetin can be used for osteoporosis-related research .
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(-)-Pinoresinol 4-O-glucoside
(-)-Pinoresinol 4-O-glucoside
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Cat. No.: HY-N0946
CAS No.: 41607-20-9
Synonyms: (-)-Pinoresinol 4-O-β-D-glucopyranoside
Category:  

Cicer arietinum L. Plants Compositae Saccharides Monosaccharides

Target:  

Glycosidase

(-)-Pinoresinol 4-O-glucoside ((-)-Pinoresinol 4-O-β-D-glucopyranoside) is a potent and orally active α-glucosidase inhibitor with an IC50 value of 48.13 µM. (-)-Pinoresinol 4-O-glucoside increases cell migration and early differentiation of pre-osteoblasts. (-)-Pinoresinol 4-O-glucoside increases protein level of BMP2, p-Smad1/5/8, RUNX2. (-)-Pinoresinol 4-O-glucoside attenuates oxidative stress, hyperglycemia and hepatic toxicity. (-)-Pinoresinol 4-O-glucoside has the potential for the research of osteoporosis and periodontal disease .
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Paeonolide (Standard)
Paeonolide (Standard)
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Cat. No.: HY-N2156R
CAS No.: 72520-92-4
Category:  

Ketones, Aldehydes, Acids Plants Paeoniaceae Paeonia suffruticosa Andr.

Target:  

Reference Standards ERK TGF-beta/Smad Wnt β-catenin JNK p38 MAPK

Paeonolide (Standard) is the analytical standard of Paeonolide (HY-N2156). This product is intended for research and analytical applications. Paeonolide, found in Paeonia suffruticosa, is an ERK1/2 activator. Paeonolide promotes early and late osteoblast differentiation, stimulates pre-osteoblast transmigration, and activates the BMP-Smad1/5/8, Wnt-β-catenin, JNK and p38 pathways. Paeonolide can be used for the research of osteoporosis, periodontitis .
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