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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
reversal agent
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "reversal agent" in MCE Product Catalog:
Cat. No.: HY-B0079
CAS No.: 343306-79-6
Synonyms: Org25969
Target:
Research Areas:
Sugammadex sodium is a synthetic γ-cyclodextrin derivative, and acts as a reversal agent for neuromuscular block. Sugammadex sodium shows nephroprotective effect in ischemia-reperfusion injury .
Synonyms: A22 hydrochloride
MreB Perturbing Compound A22 hydrochloride (A22 hydrochloride) is a reversible MreB inhibitor and antimicrobial agent that exhibits bacteriostatic activity against Escherichia coli, with low activity against Gram-positive bacteria. MreB Perturbing Compound A22 hydrochloride rapidly and reversally delocalizes MreB from the helical/circular structures in cells, impairs MreB function, and reduces the binding of MreB to the chromosomal region proximal to the replication origin. MreB Perturbing Compound A22 hydrochloride alters the cell morphology of caulobacters to round/lemon-shaped, slows caulobacter growth, blocks their cell division, and induces the formation of spherical morphology, asymmetric division, and anucleate cells in Escherichia coli. MreB Perturbing Compound A22 hydrochloride is used for studies related to bacterial rod-shaped morphology determination, chromosome segregation, and cell division mechanisms .
Cat. No.: HY-W035709
CAS No.: 485-65-4
Synonyms: Dihydrocinchonine
Target:
Cat. No.: HY-18660
CAS No.: 1438492-26-2
Synonyms: PER977
Research Areas:
Ciraparantag (PER977) is a thrombin and factor Xa inhibitor. Ciraparantag is a broad-spectrum reversal agent for anticoagulants, including low-molecular-weight heparin, unfractionated heparin, and certain direct oral anticoagulants. It is reported to antagonize the effects of all coagulants except VKAs and agratroban .
Cat. No.: HY-108739
CAS No.: 1362509-93-0
Synonyms: BI 655075
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Research Areas:
Cat. No.: HY-B0079A
CAS No.: 343306-71-8
Synonyms: Org25969 free acid
Target:
Research Areas:
Sugammadex is a synthetic γ-cyclodextrin derivative, and acts as a reversal agent for neuromuscular block. Sugammadex shows nephroprotective effect in ischemia-reperfusion injury .
Cat. No.: HY-153835
CAS No.: 959716-28-0
Pegnivacogin is a novel RNA-aptamer based factor IXa inhibitor featuring a reversal agent, anivamersen.
Cat. No.: HY-123384
CAS No.: 205535-74-6
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KR30031, a Verapamil (HY-14275) analog, is an orally active P-glycoprotein (P-gp) inhibitor. KR30031 enhances the cytotoxicity of anticancer agents by inhibiting P-gp with fewer cardiovascular adverse effects. KR30031 can be used to study multidrug resistance (MDR) reversal in cancer .
Cat. No.: HY-W035709R
CAS No.: 485-65-4
Synonyms: Dihydrocinchonine (Standard)
Cat. No.: HY-180988
Target:
Research Areas:
Heparin reversal agent-1 (Compound QA-1) is a reversal agent for Heparin (HY-17567). Heparin reversal agent-1 shows neutralization activity. Heparin reversal agent-1 completely reverses the anticoagulant activity of both unfractionated heparin and low-molecular-weight heparins, including Dalte, Enoxa, and Nadro .
Cat. No.: HY-153835A
Pegnivacogin sodium is a novel RNA-aptamer based factor IXa inhibitor featuring a reversal agent, anivamersen.
Cat. No.: HY-N12101
CAS No.: 440094-34-8
Target:
Cat. No.: HY-18660B
CAS No.: 1644388-83-9
Synonyms: PER977 acetate
Research Areas:
Ciraparantag (PER977) acetate is a thrombin and factor Xa inhibitor. Ciraparantag acetate is a broad-spectrum reversal agent for anticoagulants, including low molecular weight heparins, unfractionated heparins, and some direct oral anticoagulants, but not VKAs .
Cat. No.: HY-18660A
CAS No.: 1438492-27-3
Synonyms: PER977 TFA
Research Areas:
Ciraparantag (PER977) TFA is a thrombin and factor Xa inhibitor. Ciraparantag TFA is a broad-spectrum reversal agent for anticoagulants, including low-molecular-weight heparin, unfractionated heparin, and certain direct oral anticoagulants. It is reported to antagonize the effects of all coagulants except VKAs and agratroban .
Cat. No.: HY-121247
CAS No.: 62067-29-2
Synonyms: 5-Bromotetrandrine; BrTet; W198
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Research Areas:
Bromotetrandrine is a potent inhibitor of P-glycoprotein (P-gp)-mediated multidrug resistance (MDR). Bromotetrandrine shows significant MDR reversal activity in vitro and in vivo, which may be related to the inhibition of P-gp overexpression and the increase in intracellular accumulation of anticancer agents. Bromotetrandrine is a brominated derivative of tetrandrine, which is promising for MDR modulator for tumor assessment .
Cat. No.: HY-159818
CAS No.: 1309580-40-2
Synonyms: Adamgammadex; Aom0498
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Research Areas:
Amogammadex (Adamgammadex; Aom0498) is a modified γ-cyclodextrin (HY-W040040) derivative and neuromuscular blocking agent. Amogammadex forms inactive, tight inclusion complexes with free Rocuronium (HY-17033) and Vecuronium (HY-B0118A), and reverses the neuromuscular blockade induced by them in a concentration-dependent manner. Amogammadex can be used in research related to neuromuscular blockade reversal .
Cat. No.: HY-18660S
Synonyms: PER977-d8 tetrahydrochloride diacetate
Cat. No.: HY-163981
Target:
Research Areas:
ABCB1-IN-2 (compound 16q) is a functional inhibitor that can directly bind to the ABCB1 protein and stabilize its structure without affecting the expression and subcellular localization of ABCB1. ABCB1-IN-2 can increase the sensitivity of MCF-7/ADR cells to paclitaxel (PTX), increase the accumulation of PTX, and prevent the accumulation and excretion of luciferin Rh123 mediated by ABCB1. ABCB1-IN-2, as an ABCB1-mediated multidrug resistance (MDR) reversal agent, shows a strong ability to reverse MDR .
Cat. No.: HY-118773R
CAS No.: 22816-60-0
Synonyms: A22 hydrochloride (Standard)
Target:
Research Areas:
MreB Perturbing Compound A22 hydrochloride (Standard) is the analytical standard for MreB Perturbing Compound A22 hydrochloride (HY-118773). This product is intended for research and analytical applications. MreB Perturbing Compound A22 hydrochloride (A22 hydrochloride) is a reversible MreB inhibitor and antimicrobial agent that exhibits bacteriostatic activity against Escherichia coli, with low activity against Gram-positive bacteria. MreB Perturbing Compound A22 hydrochloride rapidly and reversally delocalizes MreB from the helical/circular structures in cells, impairs MreB function, and reduces the binding of MreB to the chromosomal region proximal to the replication origin. MreB Perturbing Compound A22 hydrochloride alters the cell morphology of caulobacters to round/lemon-shaped, slows caulobacter growth, blocks their cell division, and induces the formation of spherical morphology, asymmetric division, and anucleate cells in Escherichia coli. MreB Perturbing Compound A22 hydrochloride is used for studies related to bacterial rod-shaped morphology determination, chromosome segregation, and cell division mechanisms .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
