343306-71-8
Chemical Structure
Sugammadex
Synonym(s): Org25969 free acid
- CAS No.: 343306-71-8
- Formula:C72H112O48S8
- Molecular Weight:2002.15
InChIKey: WHRODDIHRRDWEW-XJHAQRMRSA-N
SMILES: OC(CCSC[C@@H]1OC(O[C@@H]2[C@H]([C@H](O)C(O[C@H]3[C@H](CSCCC(O)=O)OC(O[C@H]4[C@H](CSCCC(O)=O)OC5[C@@H](O)[C@@H]4O)[C@@H](O)[C@@H]3O)O[C@H]2CSCCC(O)=O)O)[C@@H](O)[C@H](O)[C@H]1OC(O[C@@H](CSCCC(O)=O)[C@H](OC6[C@@H](O)[C@H](O)[C@@H](OC7[C@@H](O)[C@H](O)[C@@H](OC8[C@@H](O)[C@H](O)[C@@H](O5)[C@H](CSCCC(O)=O)O8)[C@H](CSCCC(O)=O)O7)[C@H](CSCCC(O)=O)O6)[C@H]9O)[C@H]9O)=O
Biological Activity: Sugammadex is a synthetic γ-cyclodextrin derivative, and acts as a reversal agent for neuromuscular block. Sugammadex shows nephroprotective effect in ischemia-reperfusion injury[1][2].
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Sugammadex | Sugammadex is a synthetic γ-cyclodextrin derivative, and acts as a reversal agent for neuromuscular block. Sugammadex shows nephroprotective effect in ischemia-reperfusion injury. | |||||||||||||||||||||
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References
- [1]. de Boer HD, et al. Sugammadex, a new reversal agent for neuromuscular block induced by rocuronium in the anaesthetized Rhesus monkey. Br J Anaesth. 2006 Apr;96(4):473-9. Epub 2006 Feb 7. [Content Brief]
- [2]. Tercan M, Yılmaz İnal F, Seneldir H, Kocoglu H. Nephroprotective Efficacy of Sugammadex in Ischemia-Reperfusion Injury: An Experimental Study in a Rat Model. Cureus. 2021 Jun 17;13(6):e15726. [Content Brief]
