Pegnivacogin sodium

Cat. No.: HY-153835A: FAQs
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Pegnivacogin sodium is a novel RNA-aptamer based factor IXa inhibitor featuring a reversal agent, anivamersen.

For research use only. We do not sell to patients.

Poly(oxy-1,2-ethanediyl), α-hydro-ω-methoxy-, 5′-ester with RNA (Gm-Um-Gm-Gm-Am-(2′-deoxy-2′-fluoro)C-(2′-deoxy-2′-fluoro)U-Am-(2′-deoxy-2′-fluoro)U-Am-(2′-deoxy-2′-fluoro)C-(2′-deoxy-2′-fluoro)C-Gm-(2′-deoxy-2′-fluoro)C-Gm-(2′-deoxy-2′-fluoro)U-Am-Am-(2′-deoxy-2′-fluoro)U-Gm-(2′-deoxy-2′-fluoro)C-Um-G-Cm-(2′-deoxy-2′-fluoro)C-(2′-deoxy-2′-fluoro)U-Cm-Cm-Am-Cm-(3′→3′)-dT) 5′-[6-[[2,6-bis(carboxyamino)-1-oxohexyl]amino]hexyl hydrogen phosphate] (2:1), sodium salt

Pegnivacogin sodium Chemical Structure

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Description	Pegnivacogin sodium is a novel RNA-aptamer based factor IXa inhibitor featuring a reversal agent, anivamersen.
Molecular Weight	51.2 kDa (Approximately)
Formula	C₃₂₇H₃₉₁F₁₁N₁₁₄Na₃₁O₂₁₃P₃₁ (C_{2H_4O)n}
SMILES	[Pegnivacogin (sodium)]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (263 KB) Handling Instructions (2659 KB)
References	[1]. Staudacher DL, Putz V, Heger L, et al. Direct factor IXa inhibition with the RNA-aptamer pegnivacogin reduces platelet reactivity in vitro and residual platelet aggregation in patients with acute coronary syndromes. Eur Heart J Acute Cardiovasc Care. 2019;8(6):520-526. doi:10.1177/2048872617703065 [Content Brief]

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PegnivacoginOthersInhibitorinhibitorinhibit

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Pegnivacogin sodium