5 Results for "

superantigen

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "superantigen" in MCE Product Catalog:

Erfonrilimab
Erfonrilimab
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Cat. No.: HY-P99943
CAS No.: 2367013-69-0
Synonyms: KN-046

Target:  

PD-1/PD-L1 CTLA-4

Domaines de recherche:  

Cancer

Erfonrilimab (KN-046) is a monoclonal antibody targeting PD-L1/CTLA-4. Erfonrilimab blocks the PD-L1 and CTLA-4 pathways, thereby regulating T cell function. Erfonrilimab enhances the secretion of IL-2 in superantigen-stimulated peripheral blood mononuclear cells. Erfonrilimab inhibits tumor growth in xenograft and double gene knock-in mouse models. Erfonrilimab can be used in research related to a variety of advanced solid tumors, including non-small cell lung cancer and nasopharyngeal carcinoma.
Naptumomab
Naptumomab
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Cat. No.: HY-P99035
CAS No.: 1412892-09-1

Target:  

Inhibitory Antibodies

Domaines de recherche:  

Inflammation/Immunology Cancer

Naptumomab is a fusion protein of a tumor-targeting superantigen (TTS). Naptumomab stimulates the immune system to recognize and kill tumor cells and can be used in the study of refractory solid tumors such as renal cell carcinoma .
Toxic Shock Syndrome Toxin-1 (TSST-1) (58-78)
Toxic Shock Syndrome Toxin-1 (TSST-1) (58-78)
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Cat. No.: HY-P4984
CAS No.: 137593-46-5
Target:  

Endogenous Metabolite

Domaines de recherche:  

Infection

Toxic Shock Syndrome Toxin-1 (TSST-1) (58-78) is a superantigen exotoxin produced by Staphylococcus aureus. Toxic Shock Syndrome Toxin-1 (TSST-1) (58-78) binds to TCR and MHC II outside the antigen-presenting site, thereby inducing unconventional polyclonal lymphocyte activation, excessive cytokine production, rapid shock, multiple organ failure syndrome and even death. Toxic Shock Syndrome Toxin-1 (TSST-1) (58-78) exacerbates mammary gland inflammation and further induces mastitis. Toxic Shock Syndrome Toxin-1 (TSST-1) (58-78) is thermostable and can be transmitted to humans via food, causing toxic shock syndrome. Toxic Shock Syndrome Toxin-1 (TSST-1) (58-78) can be used in studies related to toxic shock syndrome and staphylococcal food poisoning .
SARS-CoV-2 S glycoprotein (sf9, His)
SARS-CoV-2 S glycoprotein (sf9, His)
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Cat. No.: HY-P703544
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Spike glycoprotein; E2; Peplomer protein; S; Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; superantigen
Species:  
Virus
Source:  
Sf9 insect cells
SARS-CoV-2 S glycoprotein (V987P, HEK293, Strep, His)
SARS-CoV-2 S glycoprotein (V987P, HEK293, Strep, His)
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Cat. No.: HY-P703545
Pureté:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Spike glycoprotein; E2; Peplomer protein; S; Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; superantigen
Species:  
Virus
Source:  
HEK293
Assay Types