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thiolytic cleavage

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-CE01152
    3-Oxotetradecanoyl-CoA

    		Endogenous Metabolite Others
    3-Oxotetradecanoyl-CoA is a 3-oxo fatty acyl-CoA. 3-Oxotetradecanoyl-CoA can function as a metabolite in humans, Saccharomyces cerevisiae, Escherichia coli, and mice. 3-Oxotetradecanoyl-CoA is a preferred substrate for thiolytic cleavage by P-44 (type II 3-oxoacyl-CoA thiolase) .
    3-Oxotetradecanoyl-CoA
  • HY-185585
    JNJ-27548547

    		Drug Intermediate Cancer
    JNJ-27548547, Mitomycin C (HY-13316) prodrug, is a Mitomycin C and lipophilic group conjugate. JNJ-27548547 undergoes thiolytic cleavage of its dithiobenzyl linker in the presence of reducing agents to release active substance Mitomycin C. JNJ-27548547 is formulated into pegylated liposomes (PL-MLP) with high antitumor activity in mice models .
    JNJ-27548547

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