2 Results for "

thiolytic cleavage

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "thiolytic cleavage" in MCE Product Catalog:

Cat. No.: HY-CE01152
CAS No.: 122364-86-7
Target:  

Endogenous Metabolite

Research Areas:  

Others

3-Oxotetradecanoyl-CoA is a 3-oxo fatty acyl-CoA. 3-Oxotetradecanoyl-CoA can function as a metabolite in humans, Saccharomyces cerevisiae, Escherichia coli, and mice. 3-Oxotetradecanoyl-CoA is a preferred substrate for thiolytic cleavage by P-44 (type II 3-oxoacyl-CoA thiolase) .
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Cat. No.: HY-185585
CAS No.: 303983-00-8
Target:  

Drug Intermediate

Research Areas:  

Cancer

JNJ-27548547, Mitomycin C (HY-13316) prodrug, is a Mitomycin C and lipophilic group conjugate. JNJ-27548547 undergoes thiolytic cleavage of its dithiobenzyl linker in the presence of reducing agents to release active substance Mitomycin C. JNJ-27548547 is formulated into pegylated liposomes (PL-MLP) with high antitumor activity in mice models .
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