44 Results for "

wave

" in MedChemExpress (MCE) Product Catalog:
Products (44)

44 Results for "wave" in MCE Product Catalog:

8
α-Tocopherol phosphate
α-Tocopherol phosphate
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8 Publications Verification
Referencia número: HY-16686
No. CAS: 38976-17-9
Synonyms: alpha-Tocopherol phosphate; TocP; vitamin E phosphate
Target:  

Apoptosis Reactive Oxygen Species (ROS)

Áreas de investigación:  

Cancer

α-Tocopherol phosphate is an antioxidant that protects against long-wave UVA1 induced cell death and scavenge UVA1 induced ROS in a skin cell model. α-Tocopherol phosphate exhibits angiogenesis-promoting activity .
8
α-Tocopherol phosphate disodium
α-Tocopherol phosphate disodium
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8 Publications Verification
Referencia número: HY-W127530
No. CAS: 60934-46-5
Synonyms: alpha-Tocopherol phosphate disodium; TocP disodium; Vitamin E phosphate disodium
α-Tocopherol phosphate disodium is an antioxidant that protects against long-wave UVA1 induced cell death and scavenge UVA1 induced ROS in a skin cell model. α-Tocopherol phosphate disodium exhibits angiogenesis-promoting activity .
1
Basimglurant
Basimglurant
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1 Cited Publications
Referencia número: HY-15446
No. CAS: 802906-73-6
Pureza:  ≥98.0%
Synonyms: RG7090; RO4917523
Target:  

mGluR

Áreas de investigación:  

Neurological Disease

Basimglurant (RG7090; RO4917523) is a selective, orally active, blood-brain barrier permeable negative allosteric modulator of metabotropic glutamate receptor 5 (mGluR5), with a Ki of 1.4 nM (against [ 3H]-ABP688 (HY-110141)) and 35.6 nM (against [ 3H]-MPEP (HY-14609A)). Basimglurant inhibits mGlu5-mediated signaling pathways and receptor constitutive activity, regulates dopamine levels in the nucleus accumbens, exerts anxiolytic, antidepressant-like, analgesic and arousal-promoting effects, and alters δ-wave power during non-rapid eye movement sleep. Basimglurant can be used in research on depression, fragile X syndrome, anxiety disorders, etc .
1
6-HEX
6-HEX
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1 Cited Publications
Referencia número: HY-114289
No. CAS: 155911-16-3
Pureza:  98.89%
6-HEX is one kind of light base group, the wave length is 532 nm, the wave length is 556 nm. 6-HEX can be used to record nucleic acid sequences and design optical materials. 6-HEX can be used to record nucleic acids at 543 nm radiation, and at 550 nm and 650 nm radiation (5 nm radiation), it can be used to directly locate the base of the cell group .
Scytonemin
Scytonemin
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Referencia número: HY-112356
No. CAS: 152075-98-4
Pureza:  99.53%
Category:  

Alkaloids Microorganisms Sunscreen Cosmetic Research Indole Alkaloids

Target:  

Apoptosis Reactive Oxygen Species (ROS) Polo-like Kinase (PLK)

Scytonemin is a hydrophobic alkaloid pigment that can be isolated from the outer sheath of cyanobacteria. Scytonemin has protective function against short-wave solar ultraviolet (UV) radiation, which can reduce the generation of reactive oxygen species (ROS) and the formation of DNA damage. Scytonemin also has anti-inflammatory and anti-proliferative activities, produces concentration-dependent inhibition (IC50=2.0 μM) of polo-like kinase 1 (PLK1)-mediated cdc25C phosphorylation, and plays an important role in regulating the G2/M transition in the cell cycle. It can be used in the research of cancer, acute inflammation and sunscreen cosmetics .
Dioxybenzone
Dioxybenzone
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Referencia número: HY-B0966
No. CAS: 131-53-3
Synonyms: Benzophenone-8; UV-24
Target:  

Biochemical Assay Reagents

Áreas de investigación:  

Inflammation/Immunology Cancer

Dioxybenzone (Benzophenone-8; UV-24) is an organic compound used to block UVB and short-wave UVA (ultraviolet) radiation. Dioxybenzone has orally activity. Dioxybenzone exhibits estrogenic disrupting effect. Dioxybenzone up-regulates inflammatory cytokines. Dioxybenzone can be used for cancer, reproductive system disease and inflammatory disease study .
2(5H)-Furanone
2(5H)-Furanone
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Referencia número: HY-W008270
No. CAS: 497-23-4
Synonyms: γ-Crotonolactone
Category:  

Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Bacterial

2(5H)-Furanone (γ-Crotonolactone) is an endogenous metabolite. 2(5H)-Furanone mimics N-acyl homoserine lactone signals, occupies the binding site of LuxR homologs, and interferes with quorum sensing-mediated gene regulation. 2(5H)-Furanone inhibits quorum sensing mediated by AHLs with different acyl chain lengths. 2(5H)-Furanone inhibits biofilm formation of environmental Aeromonas hydrophila strains on polystyrene plates. 2(5H)-Furanone suppresses spike-and-wave discharges in a rat model of generalized absence seizures and exhibits selective activity against absence seizures. 2(5H)-Furanone can be used in studies related to bacteria infections and generalized absence seizures.
(R)-Carvedilol
(R)-Carvedilol
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Referencia número: HY-B0006C
No. CAS: 95093-99-5
Synonyms: (R)-BM 14190
Target:  

Adrenergic Receptor Calcium Channel

Áreas de investigación:  

Cardiovascular Disease Cancer

(R)-Carvedilol ((R)-BM 14190) is the orally active R-isomer of Carvedilol (HY-B0006). (R)-Carvedilol has α-receptor blocking activity but no β-receptor blocking activity. (R)-Carvedilol inhibits spontaneous Ca 2+ waves. (R)-Carvedilol inhibits stress-induced ventricular tachycardia and delays the development of UV-induced skin tumors and reduces their malignancy .
Corticotropin-releasing factor (Sheep)
Corticotropin-releasing factor (Sheep)
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Referencia número: HY-P3538
No. CAS: 9015-71-8
Synonyms: CRH (Sheep)
Target:  

Peptides

Áreas de investigación:  

Neurological Disease

Corticotropin-releasing factor (CRH) (Sheep) is a brain-penetrant hypothalamic releasing factor and a peptide hormone with analgesic and arousal-inducing activity. Corticotropin-releasing factor (Sheep) mediates stress effects, including stress-induced analgesia. Corticotropin-releasing factor (Sheep) increases wakefulness, reduces slow wave sleep, alters EEG frequency content, stimulates ACTH and β-endorphin release, activates locomotor activity. Corticotropin-releasing factor (Sheep) can be used for the research of neurological disease .
Nonanoylcarnitine
Nonanoylcarnitine
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Referencia número: HY-N11222
No. CAS: 151109-67-0
Synonyms: C9 carnitine
Category:  

Natural Products Endogenous metabolite

Target:  

Endogenous Metabolite

Nonanoylcarnitine is a metabolite associated with chronic environmental exposure to polycyclic aromatic hydrocarbons (PAH) and fragmented QRS waves in acute myocardial infarction. Nonanoylcarnitine can be used as a potential biomarker for the metabolic outcome of PAH exposure and the prognosis of acute myocardial infarction .
MK-3697
MK-3697
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Referencia número: HY-12301
No. CAS: 1224846-01-8
Pureza:  98.83%
Target:  

Orexin Receptor (OX Receptor)

Áreas de investigación:  

Neurological Disease

MK-3697 is an orally active orexin 2 receptor (OX2R) antagonist, with an IC50 value of 16 nM and a Ki value of 1.1 nM against human OX2R. MK-3697 blocks the wake-promoting OX2R signaling pathway, reduces active wake time, and increases slow-wave sleep and rapid eye movement sleep time in mice, rats and dogs. MK-3697 can be used for research on insomnia .
Flosequinan
Flosequinan
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Referencia número: HY-119817
No. CAS: 76568-02-0
Synonyms: BTS 49465; Flosequinon
Target:  

PKC

Áreas de investigación:  

Cardiovascular Disease

Flosequinan is a balanced vasodilator. Flosequinan not only significantly reduces systemic vascular resistance, but also significantly reduces the beating component of left ventricular afterload, characteristic impedance and arterial wave reflection, which can be used in the research of acute heart failure .
BMY-21502
BMY-21502
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Referencia número: HY-106809
No. CAS: 123259-91-6
Synonyms: BMS-181168
Target:  

Drug Derivative

Áreas de investigación:  

Neurological Disease

BMY-21502 (BMS-181168) is a pyrrolidinone derivative with memory- and cognition-enhancing activities. BMS-181168 attenuates hypoxia-induced deterioration in brain function, as delta/theta decreases, alpha activity increases and the centroid of the combined delta/theta waves is accelerated .
5-Nitro BAPTA tetramethyl ester
5-Nitro BAPTA tetramethyl ester
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Referencia número: HY-D1637
No. CAS: 172646-43-4
Target:  

Fluorescent Dye

Áreas de investigación:  

Others

5-Nitro BAPTA tetramethyl ester is a calcium chelator. 5-Nitro BAPTA tetramethyl ester involves in the two-photon probe synthesis, and is used for real-time imaging of intracellular calcium ions, calcium waves monitoring at a depth of 100-300 μm in liver tissues for 1100-4000 s. 5-Nitro BAPTA tetramethyl ester, together with fluorescent compound 2-Me-substituted TM, can be used to form a red fluorescent probe (CaTM-2 AM) .
ICG-alkyne
ICG-alkyne
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Referencia número: HY-151704
No. CAS: 1622335-41-4
Pureza:  99.17%
ICG-alkyne is a short-wave infrared (SWIR)-emitting cyanine fluorescent probe based on alkyne-derivatized indocyanine green. ICG-alkyne can undergo click chemistry reaction to conjugate with antibody molecules via binding to the azide groups introduced into antibodies. ICG-alkyne enables SWIR fluorescent molecular imaging of breast tumors in living mice. ICG-alkyne can be used in breast cancer-related research .
EYE-002
EYE-002
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Referencia número: HY-175663
Target:  

RPE65

Áreas de investigación:  

Metabolic Disease

EYE-002 is a RPE65 inhibitor with an IC50 of 69 nM. EYE-002 promotes recovery of scotopic ERG a-/b-wave amplitudes. EYE-002 regulates the visual cycle in mice by reducing 11-cis-retinal (11cRAL) (HY-116711) synthesis and increasing all-trans-retinyl esters (atREs). EYE-002 exerts protective effects against photic retinal damage in mice. EYE-002 can be used for the study of visual cycle-associated retinopathies, such as Stargardt disease type 1 (STGD1) .
EYE-003
EYE-003
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Referencia número: HY-175664
Target:  

RPE65

Áreas de investigación:  

Metabolic Disease

EYE-003 is an orally active RPE65 inhibitor with an IC50 of 102 nM. EYE-003 regulates the visual cycle in mice by reducing 11-cis-retinal (11cRAL) (HY-116711) synthesis and increasing all-trans-retinyl esters (atREs). EYE-003 suppresses scotopic ERG b-wave amplitude and exerts protective effects against retinal degeneration in Abca4 ⁻/⁻ Rdh8 ⁻/⁻ mice (a STGD1 model) by reducing retinal autofluorescent puncta and preserving outer nuclear layer (ONL) thickness in a dose-dependent manner. EYE-003 can be used for the study of visual cycle-associated retinopathies, such as Stargardt disease type 1 (STGD1) .
BMT-108908
BMT-108908
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Referencia número: HY-117467
No. CAS: 1801151-15-4
Target:  

iGluR

Áreas de investigación:  

Neurological Disease

BMT-108908 is a negative allosteric modulator with selective activity on the NR2B subtype of the NMDA receptor. BMT-108908 has been shown to damage cognition in research, affecting cognitive functions in multiple areas. BMT-108908 failed to show a significant impact on the γ wave power of the EEG in the experiment, but it had a significant inhibitory and enhancement effect on the β wave and δ wave power .
Wasf1 Mouse Pre-designed siRNA Set A
Wasf1 Mouse Pre-designed siRNA Set A
Referencia número: HY-RS22917
Target:  

Small Interfering RNA (siRNA)

Áreas de investigación:  

Others

Wasf1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Wasf1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Enciprazine
Enciprazine
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Referencia número: HY-19682
No. CAS: 68576-86-3
Target:  

5-HT Receptor Adrenergic Receptor

Áreas de investigación:  

Neurological Disease

Enciprazine is an orally active non-benzodiazepine anxiolytic. Enciprazine acts as an agonist of 5-HT1A receptor (5-HT1AR) and an antagonist of α1-adrenergic receptor (α1-adrenergic receptor) . Enciprazine induces drug-related electroencephalogram changes by reducing the average power of δ waves and θ waves, and increasing the average power of α waves and fast β waves. Enciprazine exhibits anti-aggressive activity, with only weak sedative and ataxic effects. Enciprazine regulates plasma corticosterone levels and activates the hypothalamic-pituitary-adrenal axis. Enciprazine can be used in research related to anxiety disorders, generalized anxiety syndrome and psychosis .
Assay Types