1. GPCR/G Protein
    Neuronal Signaling
  2. Adrenergic Receptor
  3. (R)-Carvedilol

(R)-Carvedilol (Synonyms: (R)-BM 14190)

Cat. No.: HY-B0006C Purity: 99.05% ee.: 98.97%
Handling Instructions

(R)-Carvedilol ((R)-BM 14190), the R-enantiomer of Carvedilol, is a non-selective β/α-1 blocker. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX).

For research use only. We do not sell to patients.

(R)-Carvedilol Chemical Structure

(R)-Carvedilol Chemical Structure

CAS No. : 95093-99-5

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5 mg USD 240 In-stock
Estimated Time of Arrival: December 31
10 mg USD 400 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of (R)-Carvedilol:

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Description

(R)-Carvedilol ((R)-BM 14190), the R-enantiomer of Carvedilol, is a non-selective β/α-1 blocker. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX)[1].

IC50 & Target

β/α-1 adrenergic receptor[1]

Molecular Weight

406.47

Formula

C₂₄H₂₆N₂O₄

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 220 mg/mL (541.25 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4602 mL 12.3010 mL 24.6021 mL
5 mM 0.4920 mL 2.4602 mL 4.9204 mL
10 mM 0.2460 mL 1.2301 mL 2.4602 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 5.5 mg/mL (13.53 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: 5.5 mg/mL (13.53 mM); Suspended solution; Need ultrasonic

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 5.5 mg/mL (13.53 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.05% ee.: 98.97%

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Product Name:
(R)-Carvedilol
Cat. No.:
HY-B0006C
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