Silperisone hydrochloride
Silperisone hydrochloride is an organosilicone compound similar to tolperisone that has centrally acting muscle relaxant properties. Silperisone (hydrochloride) is a sodium channel protein type 2 alpha channel blocker that blocks sodium and calcium channels in cells, reduces muscle cell excitability and contraction, reduces peripheral tone, and acts as a muscle relaxant and peripheral vascular dilator. Silperisone (hydrochloride) is used to study recurrent painful myoclonus due to spinal cord injury, abnormal hypertonia due to cerebrovascular disease, myotonia symptoms, pyramidal tonia syndrome, multiple sclerosis myospasm, and myelitis.
For research use only. We do not sell to patients.
- CAS No.: 140944-30-5
- Formula: C15H25ClFNSi
- Molecular Weight:301.90
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 140944-30-5
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Molecular Weight 301.90
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Formula C15H25ClFNSi
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SMILES
FC1=CC=C(C[Si](C)(CN2CCCCC2)C)C=C1.Cl
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Synonyms
RGH-5002
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Farkas S, et al. Simple pharmacological test battery to assess efficacy and side effect profile of centrally acting muscle relaxant drugs[J]. Journal of Pharmacological and Toxicological methods, 2005, 52(2): 264-273. [Content Brief]
[2]. Kocsis P, et al. Tolperisone-type drugs inhibit spinal reflexes via blockade of voltage-gated sodium and calcium channels[J]. Journal of Pharmacology and Experimental Therapeutics, 2005, 315(3): 1237-1246. [Content Brief]
[3]. Farkas S, et al. Silperisone: a centrally acting muscle relaxant[J]. CNS Drug Reviews, 2006, 12(3‐4): 218-235. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Silperisone hydrochloride Related Classifications
HY-127004 Related Classifications
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