1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. β-D-glucuronide-pNP-carbonate

β-D-glucuronide-pNP-carbonate 

Cat. No.: HY-136329
Handling Instructions

β-D-glucuronide-pNP-carbonate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

β-D-glucuronide-pNP-carbonate Chemical Structure

β-D-glucuronide-pNP-carbonate Chemical Structure

CAS No. : 894095-98-8

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Description

β-D-glucuronide-pNP-carbonate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Molecular Weight

913.83

Formula

C₄₅H₄₃N₃O₁₈

CAS No.

894095-98-8

SMILES

O=C(NCCC(NC(C=C1COC(OC(C=C2)=CC=C2[N+]([O-])=O)=O)=C(C=C1)O[[email protected]](O[[email protected]@H]3C(OC)=O)[[email protected]@H]([[email protected]]([[email protected]@H]3OC(C)=O)OC(C)=O)OC(C)=O)=O)OCC4C5=CC=CC=C5C6=CC=CC=C46

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

β-D-glucuronide-pNP-carbonateADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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β-D-glucuronide-pNP-carbonate
Cat. No.:
HY-136329
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