Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc
Based on 1 Customer Validation
Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 98.01%
- CAS No.: 894096-02-7
- Formula: C38H40N2O14
- Molecular Weight:748.73
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
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Glycosidase Cleavable Linker |
Cleavable Linker |
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 894096-02-7
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Appearance Solid
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Molecular Weight 748.73
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Formula C38H40N2O14
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Color White to light yellow
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SMILES
O=C(OC)[C@@H](O1)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC2=CC=C(CO)C=C2NC(CCNC(OCC3C4=C(C5=C3C=CC=C5)C=CC=C4)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (133.56 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.3356 mL | 6.6780 mL | 13.3559 mL | 33.3899 mL |
| 5 mM | 0.2671 mL | 1.3356 mL | 2.6712 mL | 6.6780 mL | |
| 10 mM | 0.1336 mL | 0.6678 mL | 1.3356 mL | 3.3390 mL | |
| 15 mM | 0.0890 mL | 0.4452 mL | 0.8904 mL | 2.2260 mL | |
| 20 mM | 0.0668 mL | 0.3339 mL | 0.6678 mL | 1.6695 mL | |
| 25 mM | 0.0534 mL | 0.2671 mL | 0.5342 mL | 1.3356 mL | |
| 30 mM | 0.0445 mL | 0.2226 mL | 0.4452 mL | 1.1130 mL | |
| 40 mM | 0.0334 mL | 0.1669 mL | 0.3339 mL | 0.8347 mL | |
| 50 mM | 0.0267 mL | 0.1336 mL | 0.2671 mL | 0.6678 mL | |
| 60 mM | 0.0223 mL | 0.1113 mL | 0.2226 mL | 0.5565 mL | |
| 80 mM | 0.0167 mL | 0.0835 mL | 0.1669 mL | 0.4174 mL | |
| 100 mM | 0.0134 mL | 0.0668 mL | 0.1336 mL | 0.3339 mL |
Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc Related Classifications
HY-131087 Related Classifications
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