1. Cell Cycle/DNA Damage
    Cytoskeleton
  2. Microtubule/Tubulin
  3. 10-Deacetyltaxol

10-Deacetyltaxol (Synonyms: 10-Deacetylpaclitaxel)

Cat. No.: HY-N1391
Handling Instructions

10-Deacetyltaxol (10-Deacetylpaclitaxel) is a taxane derivative isolated from Taxus wallichiana Zucc. 10-Deacetyltaxol (10-Deacetylpaclitaxel) promotes the polymerization of tubulin and to inhibit the depolymerization of microtubules induced by cold or by calcium ions in vitro. 10-Deacetyltaxol (10-Deacetylpaclitaxel) exhibits cytotoxicity in human glial and neuroblastoma cell-lines.

For research use only. We do not sell to patients.

10-Deacetyltaxol Chemical Structure

10-Deacetyltaxol Chemical Structure

CAS No. : 78432-77-6

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Description

10-Deacetyltaxol (10-Deacetylpaclitaxel) is a taxane derivative isolated from Taxus wallichiana Zucc[1]. 10-Deacetyltaxol (10-Deacetylpaclitaxel) promotes the polymerization of tubulin and to inhibit the depolymerization of microtubules induced by cold or by calcium ions in vitro[2]. 10-Deacetyltaxol (10-Deacetylpaclitaxel) exhibits cytotoxicity in human glial and neuroblastoma cell-lines[3].

IC50 & Target

tubulin[2]

Molecular Weight

811.87

Formula

C₄₅H₄₉NO₁₃

CAS No.

78432-77-6

SMILES

CC(O[[email protected]]12[[email protected]@]([[email protected]]3([[email protected]@H](O)C[[email protected]@]1([H])OC2)C)([H])[[email protected]@H]([[email protected]]4(C(C)(C([[email protected]@H](O)C3=O)=C(C)[[email protected]@H](OC([[email protected]](O)[[email protected]](C5=CC=CC=C5)NC(C6=CC=CC=C6)=O)=O)C4)C)O)OC(C7=CC=CC=C7)=O)=O

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10-Deacetyltaxol
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HY-N1391
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