10-Deacetyltaxol (Standard)
10-Deacetyltaxol (Standard) (10-Deacetylpaclitaxel (Standard)) is the analytical standard of 10-Deacetyltaxol (HY-N1391). This product is intended for research and analytical applications. 10-Deacetyltaxol (10-Deacetylpaclitaxel) is a taxane derivative found in Taxus wallichiana Zucc. and exhibits cytotoxicity against human neurotumor cell lines. It shows a concentration-dependent cytotoxic effect on cancer cells and demonstrates activity in the mouse leukemia system. 10-Deacetyltaxol can be used for research on neuroblastoma, glioblastoma multiforme, and lymphocytic leukemia.
For research use only. We do not sell to patients.
- CAS No.: 78432-77-6
- Formula: C45H49NO13
- Molecular Weight:811.87
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 78432-77-6
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Molecular Weight 811.87
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Formula C45H49NO13
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SMILES
CC(O[C@]12[C@@]([C@]3([C@@H](O)C[C@@]1([H])OC2)C)([H])[C@@H]([C@]4(C(C)(C([C@@H](O)C3=O)=C(C)[C@@H](OC([C@H](O)[C@H](C5=CC=CC=C5)NC(C6=CC=CC=C6)=O)=O)C4)C)O)OC(C7=CC=CC=C7)=O)=O
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Synonyms
10-Deacetylpaclitaxel (Standard)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[2]. Helson L, et al. Cephalomannine and 10-deacetyltaxol cytotoxicity in human glial and neuroblastoma cell-lines. International journal of oncology. 1993 Feb;2(2):297-9. [Content Brief]
[3]. McLaughlin JL, et al. 19-Hydroxybaccatin III, 10-deacetylcephalomannine, and 10-deacetyltaxol: new antitumor taxanes from Taxus wallichiana. J Nat Prod. 1981 May-Jun;44(3):312-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- 10-Deacetyltaxol (Standard)
- 78432-77-6
- 10-Deacetylpaclitaxel (Standard)
- Reference Standards
- Endogenous Metabolite
- human neural tumor cell lines
- neuroblastoma
- Pichia pastoris GS115-3.5K-P1-2
- β-xylosidase
- Taxus wallichiana Zucc.
- mouse leukemia systems
- lymphocytic leukemia
- engineered yeast
- glioblastoma multiforme
- Lentinula edodes
- Inhibitor
- inhibitor
- inhibit