1. Membrane Transporter/Ion Channel
  2. Monocarboxylate Transporter
  3. 7ACC2

7ACC2 

Cat. No.: HY-D0713 Purity: 99.44%
Handling Instructions

7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for inhibition of [14C]-lactate influx; new antitumor treatment targeting lactate transport in cancer cells.

For research use only. We do not sell to patients.

7ACC2 Chemical Structure

7ACC2 Chemical Structure

CAS No. : 1472624-85-3

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 327 In-stock
Estimated Time of Arrival: December 31
2 mg USD 192 In-stock
Estimated Time of Arrival: December 31
5 mg USD 288 In-stock
Estimated Time of Arrival: December 31
10 mg USD 528 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1680 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2520 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for inhibition of [14C]-lactate influx; new antitumor treatment targeting lactate transport in cancer cells. IC50 value: 11 nM ([14C]-lactate influx) [1] Target: MCT inhibitor; lactate transport inhibitor 7ACC2 did not influence the prothrombin time which, together with a good in vitro ADME profile, supports the potential of this new family of compounds to act as anticancer drugs through inhibition of lactate flux.

Molecular Weight

309.32

Formula

C₁₈H₁₅NO₄

CAS No.

1472624-85-3

SMILES

CN(C1=CC=C(C=C(C(O)=O)C(O2)=O)C2=C1)CC3=CC=CC=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 46 mg/mL (148.71 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2329 mL 16.1645 mL 32.3290 mL
5 mM 0.6466 mL 3.2329 mL 6.4658 mL
10 mM 0.3233 mL 1.6164 mL 3.2329 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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KeyWords:

7ACC2 | Monocarboxylate Transporter | Inhibitor | inhibitor | inhibit

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Product name:
7ACC2
Cat. No.:
HY-D0713
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