2. Immunology/Inflammation
  3. CD73
  4. CD73-IN-1

CD73-IN-1 is an inhibitor of CD73 which can be used in the treatment of cancer extracted from patent WO 2017153952 A1, example 80.

Para uso exclusivo en investigación. No vendemos a pacientes.

CD73-IN-1

CD73-IN-1 Estructura química

No. CAS : 2132396-40-6

Tamaño Precio Stock Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
1 mg En stock
5 mg En stock
10 mg En stock
25 mg En stock
50 mg   Obtener un presupuesto  
100 mg   Obtener un presupuesto  

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Revisión del cliente

Based on 1 publication(s) in Google Scholar

Other Forms of CD73-IN-1:

CD73-IN-1 Related Antibodies

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Descripciòn

CD73-IN-1 is an inhibitor of CD73 which can be used in the treatment of cancer extracted from patent WO 2017153952 A1, example 80.

IC50 & Target

CD73[1]
Peso molecular

371.41

Fòrmula

C18H17N3O4S
No. CAS
Appearance

Solid

Color

White to off-white

SMILES

O=C(N)C1=CC(S(=O)(NC2=CC3=C(C=C2)C=C(C4CC4)N3)=O)=CC=C1O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvente y solubilidad
In Vitro: 

DMSO : 100 mg/mL (269.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6924 mL 13.4622 mL 26.9244 mL
5 mM 0.5385 mL 2.6924 mL 5.3849 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6924 mL 13.4622 mL 26.9244 mL 67.3111 mL
5 mM 0.5385 mL 2.6924 mL 5.3849 mL 13.4622 mL
10 mM 0.2692 mL 1.3462 mL 2.6924 mL 6.7311 mL
15 mM 0.1795 mL 0.8975 mL 1.7950 mL 4.4874 mL
20 mM 0.1346 mL 0.6731 mL 1.3462 mL 3.3656 mL
25 mM 0.1077 mL 0.5385 mL 1.0770 mL 2.6924 mL
30 mM 0.0897 mL 0.4487 mL 0.8975 mL 2.2437 mL
40 mM 0.0673 mL 0.3366 mL 0.6731 mL 1.6828 mL
50 mM 0.0538 mL 0.2692 mL 0.5385 mL 1.3462 mL
60 mM 0.0449 mL 0.2244 mL 0.4487 mL 1.1219 mL
80 mM 0.0337 mL 0.1683 mL 0.3366 mL 0.8414 mL
100 mM 0.0269 mL 0.1346 mL 0.2692 mL 0.6731 mL
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CD73-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CD73-IN-12132396-40-6CD73ecto-5′-nucleotidase, NT5EInhibitorinhibitorinhibit

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Nombre del producto:
CD73-IN-1
Cat. No.:
HY-103695
Cantidad:
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