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Cat. No.: HY-100747R

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PSB-12379 (Standard)

PSB-12379 (Standard) is the analytical standard of PSB-12379 (HY-100747). This product is intended for research and analytical applications. PSB-12379, a nucleotide analogue, is a potent Ecto-5'-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human).

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CAS No.: 1802226-78-3
화학식: C₁₈H₂₃N₅O₉P₂
분자량:515.35

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

PSB-12379 (Standard) Chemical Structure

CAS No.: 1802226-78-3

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Antibody-Drug Conjugates

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

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신청

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 1802226-78-3
분자량 515.35
화학식 C₁₈H₂₃N₅O₉P₂
SMILES

O=P(O)(O)CP(OC[C@H]1O[C@@H](N2C=NC3=C(NCC4=CC=CC=C4)N=CN=C32)[C@H](O)[C@@H]1O)(O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Bhattarai S, et al. α,β-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5'-Nucleotidase (CD73) Inhibitors. J Med Chem. 2015 Aug 13;58(15):6248-63. [Content Brief]

[2]. X-Ray Co-Crystal Structure Guides the Way to Subnanomolar Competitive Ecto-5 -Nucleotidase (CD73) Inhibitors for Cancer Immunotherapy Sanjay Bhattarai. Adv. Therap. 2019, 2, 1900075.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Chemical Information
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상품명:
Cat. No.:
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MCE Japan Authorized Agent:

상품명:
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PSB-12379 (Standard)

PSB-12379

CD73-IN-1

AB-680

MethADP

CD73-IN-1 (Standard)

CD73-IN-4

CD73-IN-3

Oleclumab

OP-5244

CD73-IN-5

Uliledlimab

MethADP sodium

Product Information

Chemical Information

순도&문서

References

Calculators

Help & FAQs

PSB-12379 (Standard)

PSB-12379

CD73-IN-1

AB-680

MethADP

CD73-IN-1 (Standard)

CD73-IN-4

CD73-IN-3

Oleclumab

OP-5244

CD73-IN-5

Uliledlimab

MethADP sodium

Product Information

Chemical Information

순도&문서

References

Calculators

Help & FAQs

PSB-12379 (Standard) Related Classifications

HY-100747R Related Classifications