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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
CPT11
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "CPT11" in MCE Product Catalog:
81
81 Publications Verification
Cat. No.: HY-16562
CAS No.: 97682-44-5
Synonyms: (+)-Irinotecan; CPT-11; VAL-413free base
Target:
Research Areas:
Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex .
81
81 Publications Verification
Cat. No.: HY-16562A
CAS No.: 100286-90-6
Synonyms: (+)-Irinotecan hydrochloride; CPT-11 hydrochloride; VAL-413
Category:
Alkaloids Quinoline Alkaloids Camptotheca acuminata Decne. Plants Nyssaceae Disease Research Fields Cancer
Target:
81
81 Publications Verification
Cat. No.: HY-16568
CAS No.: 136572-09-3
Synonyms: (+)-Irinotecan hydrochloride trihydrate; CPT-11 hydrochloride trihydrate
Target:
Research Areas:
Irinotecan hydrochloride trihydrate ((+)-Irinotecan hydrochloride trihydrate) is a topoisomerase I inhibitor with antitumor activity .
Synonyms: APC
Target:
Research Areas:
RPR121056 (APC) is a metabolite of Irinotecan (CPT-11), which is generated by CYP3A4. Irinotecan (CPT-11) is an antineoplastic agent that inhibits topoisomerase type I, causing cell death, and is widely used in the treatment of colorectal cancer. Irinotecan also directly inhibits AChE .
Cat. No.: HY-100638
CAS No.: 185304-42-1
Synonyms: NPC
Target:
Research Areas:
RPR132595A (NPC) is an active metabolite of CPT-11, which is generated by cytochrome P-450 3A4 (CYP3A4) and finally excreted through urine .
Cat. No.: HY-100620R
CAS No.: 181467-56-1
Synonyms: APC (Standard)
Research Areas:
RPR121056 (Standard) is the analytical standard of RPR121056. This product is intended for research and analytical applications. RPR121056 (APC) is a metabolite of Irinotecan (CPT-11), which is generated by CYP3A4. Irinotecan (CPT-11) is an antineoplastic agent that inhibits topoisomerase type I, causing cell death, and is widely used in the treatment of colorectal cancer. Irinotecan also directly inhibits AChE[1].
Cat. No.: HY-149291
CAS No.: 3033712-80-7
ATM Inhibitor-7 is a potent and selective ataxia-telangiectasia mutated (ATM) inhibitor with an IC50 value of 1.0 nM. ATM Inhibitor-7 induces Apoptosis and cell cycle arrest at G2/M phase when combinanted with CPT-11 (HY-16562). ATM Inhibitor-7 combines with CPT-11 shows antitumor activity .
Cat. No.: HY-100638A
Purity: 99.46%
Synonyms: NPC hydrochloride
Target:
Research Areas:
RPR132595A (NPC) hydrochloride is an active metabolite of CPT-11, which is generated by cytochrome P-450 3A4 (CYP3A4) and finally excreted through urine .
Cat. No.: HY-145513
CAS No.: 1084888-82-3
Target:
Research Areas:
CL2-MMT-SN38 is a SN-38 derivative. SN-38, an anticancer agent, is an active metabolite of the Topoisomerase I inhibitor Irinotecan (CPT-11) .
Cat. No.: HY-132545S
CAS No.: 1217625-98-3
Synonyms: NPC-d3
Cat. No.: HY-120638
CAS No.: 406913-72-2
Target:
Research Areas:
BMS-250749 is a topoisomerase I (Top I) inhibitor of the fluoroglycosyl-3,9-difluoroindolecarbazole class. BMS-250749 exhibits potent cytotoxicity and selectivity, and shows curative antitumor activity against Lewis lung cancer. BMS-250749 exhibits broad-spectrum antitumor activity superior to CPT-11 in certain preclinical xenograft models. .
Cat. No.: HY-132561S
CAS No.: 1217816-76-6
Synonyms: APC-d3
Cat. No.: HY-16568R
CAS No.: 136572-09-3
Synonyms: (+)-Irinotecan hydrochloride trihydrate (Standard); CPT-11 hydrochloride trihydrate (Standard)
Research Areas:
Irinotecan (hydrochloride trihydrate) (Standard) is the analytical standard of Irinotecan (hydrochloride trihydrate). This product is intended for research and analytical applications. Irinotecan hydrochloride trihydrate ((+)-Irinotecan hydrochloride trihydrate) is a topoisomerase I inhibitor with antitumor activity .
Cat. No.: HY-16562AR
CAS No.: 100286-90-6
Synonyms: (+)-Irinotecan hydrochloride (Standard); CPT-11 hydrochloride (Standard); VAL-413 (Standard)
Cat. No.: HY-16562R
CAS No.: 97682-44-5
Synonyms: (+)-Irinotecan (Standard); CPT-11 (Standard); VAL-413free base (Standard)
Research Areas:
Irinotecan (Standard) is the analytical standard of Irinotecan. This product is intended for research and analytical applications. Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex .
Cat. No.: HY-16562AS
CAS No.: 718612-73-8
Synonyms: (+)-Irinotecan-d5 (hydrochloride; CPT-11-d5 hydrochloride; VAL-413-d5
Cat. No.: HY-16562S
CAS No.: 718613-28-6
Synonyms: (+)-Irinotecan-d10; CPT-11-d10; VAL-413-d10free base
Cat. No.: HY-16562S2
CAS No.: 718613-65-1
Synonyms: (+)-Irinotecan-13C6; CPT-11-13C6; VAL-413-13C6 free base
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
