BMS-250749
BMS-250749 is a topoisomerase I (Top I) inhibitor of the fluoroglycosyl-3,9-difluoroindolecarbazole class. BMS-250749 exhibits potent cytotoxicity and selectivity, and shows curative antitumor activity against Lewis lung cancer. BMS-250749 exhibits broad-spectrum antitumor activity superior to CPT-11 in certain preclinical xenograft models..
For research use only. We do not sell to patients.
- CAS No.: 406913-72-2
- Formula: C26H18F3N3O6
- Molecular Weight:525.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Topoisomerase Isoforms
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Biological Activity
Topoisomerase I[1]
Chemical Information
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CAS No. 406913-72-2
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Molecular Weight 525.43
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Formula C26H18F3N3O6
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SMILES
O=C1NC(C2=C1C3=C(NC4=C3C=C(C=C4)F)C5=C2C6=C(C=CC(F)=C6)N5[C@H]7[C@H](O)[C@@H](O)[C@@H]([C@H](O7)CO)F)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BMS-250749 Related Classifications
HY-120638 Related Classifications
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