1. Cell Cycle/DNA Damage
    Neuronal Signaling
  2. Topoisomerase
    AChE
  3. RPR121056

RPR121056 (Synonyms: APC)

Cat. No.: HY-100620
Handling Instructions

RPR121056 (APC) is a metabolite of Irinotecan (CPT-11), which is generated by CYP3A4. Irinotecan (CPT-11) is an antineoplastic agent that inhibits topoisomerase type I, causing cell death, and is widely used in the treatment of colorectal cancer. Irinotecan also directly inhibits AChE.

For research use only. We do not sell to patients.

RPR121056 Chemical Structure

RPR121056 Chemical Structure

CAS No. : 181467-56-1

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

View All Topoisomerase Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

RPR121056 (APC) is a metabolite of Irinotecan (CPT-11), which is generated by CYP3A4. Irinotecan (CPT-11) is an antineoplastic agent that inhibits topoisomerase type I, causing cell death, and is widely used in the treatment of colorectal cancer. Irinotecan also directly inhibits AChE[1].

IC50 & Target

Topoisomerase type I[1]; AChE[1]

Clinical Trial
Molecular Weight

618.68

Formula

C₃₃H₃₈N₄O₈

CAS No.

181467-56-1

SMILES

O=C(N1CCC(NCCCCC(O)=O)CC1)OC2=CC=C3N=C4C(CN5C(C(COC([[email protected]@]6(CC)O)=O)=C6C=C54)=O)=C(CC)C3=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

RPR121056APCRPR 121056RPR-121056TopoisomeraseAChEAcetylcholinesteraseIrinotecanmetaboliteantineoplasticCYP3A4topoisomerase-IInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
RPR121056
Cat. No.:
HY-100620
Quantity:
MCE Japan Authorized Agent: