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Hydroxyethyl cellulose  (Synonyms: Hydroxyethyl pectin glycosidase)

Cat. No.: HY-B2221B
COA Handling Instructions

Hydroxyethyl cellulose is a non-ionic, modified cellulose polymer used as a thickening agent for aqueous cosmetic and personal care formulations.

For research use only. We do not sell to patients.

Hydroxyethyl cellulose Chemical Structure

Hydroxyethyl cellulose Chemical Structure

CAS No. : 9004-62-0

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Based on 1 publication(s) in Google Scholar

Other Forms of Hydroxyethyl cellulose:

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Hydroxyethyl cellulose

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review


Hydroxyethyl cellulose is a non-ionic, modified cellulose polymer used as a thickening agent for aqueous cosmetic and personal care formulations.

In Vitro

Stabilization of graphene oxide in physiological solution is performed using hydroxyethyl cellulose to make the resultant nanohybrid suitable for targeted drug delivery purposes. Hydroxyethyl cellulose effectively stabilizes graphene oxid in electrolyte solutions and the mechanism of stabilization appears to be depended on hydroxyethyl cellulose content. Hydroxyethyl cellulose content in the nanohybrid plays an important role in final application to make it applicable either as a carrier for controllable drug release or as a folate-targeted drug carrier[1]. Hydroxyethyl cellulose shows superior cryoprotective effects on LDH during freeze thawing, and considerable lyoprotective effects during the freeze drying process. Annealing has limited influence on the stabilizing effect of hydroxyethyl cellulose. The extensive reconstitution times of the hydroxyethyl cellulose lyophilisates could be greatly improved by incorporation of the surfactant Tween 80 into the formulations prior to freeze drying[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.




White to off-white


[Cellulose glycol]


Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 9.09 mg/mL (warming and heat to 93°C)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)


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Concentration (final)


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In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 50 mg/mL (Infinity mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:



Animal weight
(per animal)


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(per animal)


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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
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Hydroxyethyl cellulose Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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