JND3229 

Cat. No.: HY-119944
Handling Instructions

JND3229 is a new highly potent EGFRC797S reversible inhibitor with IC50 value of 5.8 nM, and also potently suppressed EGFRL858R/T790M and EGFRWT with IC50 values of 30.5 and 6.8 nM.

For research use only. We do not sell to patients.

JND3229 Chemical Structure

JND3229 Chemical Structure

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

JND3229 is a new highly potent EGFRC797S reversible inhibitor with IC50 value of 5.8 nM, and also potently suppressed EGFRL858R/T790M and EGFRWT with IC50 values of 30.5 and 6.8 nM.

References
Molecular Weight

617.18

Formula

C₃₃H₄₁ClN₈O₂

SMILES

CC1=CC(NC2=NC(N([[email protected]@H]3CC[[email protected]@H](NC(CC)=O)CC3)C(N(C4=C(Cl)C=CC=C4)C5)=O)=C5C=N2)=CC=C1N6CCN(C)CC6

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
JND3229
Cat. No.:
HY-119944
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JND3229

Cat. No.: HY-119944