Miriplatin
Based on 3 publication(s) in Google Scholar
Miriplatin (SM-11355) is a chemotherapy agent which belongs to the class of alkylating agents.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 141977-79-9
- Formula: C34H68N2O4Pt
- Molecular Weight:764.00
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
-
HY-13585
CarmustineDNA/RNA Alkylator -
HY-17574
Thio-TEPABacterial Inhibitor -
HY-34758
N-Nitroso-N-methylureaCarcinogen Agent -
HY-B0181
AltretamineDNA Alkylator/Crosslinker -
HY-16503
TreosulfanAlkylating Cytotoxic Agent -
HY-17576
SatraplatinDNA Alkylator -
HY-13747
SemustineAntitumor Alkylating Agent -
HY-17420A
Cyclophosphamide hydrateAlkylating Agent -
HY-13593
ChlorambucilDNA Alkylator -
HY-13585R
Carmustine (Standard)DNA/RNA Alkylator -
HY-17574R
Thio-TEPA (Standard)Bacterial Inhibitor -
HY-B0181R
Altretamine (Standard)DNA Alkylator/Crosslinker
Publications Citing Use of MedChemExpress (MCE) Miriplatin
More
Biological Activity
Description
In Vitro
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 141977-79-9
-
Appearance Solid
-
Molecular Weight 764.00
-
Formula C34H68N2O4Pt
-
Color White to off-white
-
SMILES
NC1CCCCC1N.[O-]C(CCCCCCCCCCCCC)=O.[O-]C(CCCCCCCCCCCCC)=O.[Pt+2]
-
Synonyms
SM-11355
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (3)
-
Journal Impact Factor
-
Most Recent
-
J Control Release
Nanoparticle-delivered miriplatin ultrasmall dots suppress triple negative breast cancer lung metastasis by targeting circulating tumor cells. [Abstract]2021 Jan 10:329:833-846. PMID: 33045314 -
J Mol Med (Berl)
2019 Aug;97(8):1183-1193. PMID: 31201471 -
Solvent & Solubility
In Vitro:
chloroform : 43.33 mg/mL (56.71 mM; Need ultrasonic; DMSO can inactivate Miriplatin's activity)
Acetone : < 1 mg/mL (insoluble; DMSO can inactivate Miriplatin's activity)
DMF : < 1 mg/mL (insoluble; DMSO can inactivate Miriplatin's activity)
H2O : < 0.1 mg/mL (insoluble; DMSO can inactivate Miriplatin's activity)
* Miriplatin is usually formulated as a suspension.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (274 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
[1]. Kishimoto S, et al. Antitumor effects of a novel lipophilic platinum complex (SM-11355) against a slowly-growing rat hepatic tumor after intra-hepatic arterial administration. Biol Pharm Bull. 2000 Mar;23(3):344-8. [Content Brief]
[2]. Hanada M, et al. Intra-hepatic arterial administration with miriplatin suspended in an oily lymphographic agent inhibits the growth of tumors implanted in rat livers by inducing platinum-DNA adducts to form and massive apoptosis. Cancer Chemother Pharmacol. 2009 Aug;64(3):473-83. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| chloroform | 1 mM | 1.3089 mL | 6.5445 mL | 13.0890 mL | 32.7225 mL |
| 5 mM | 0.2618 mL | 1.3089 mL | 2.6178 mL | 6.5445 mL | |
| 10 mM | 0.1309 mL | 0.6545 mL | 1.3089 mL | 3.2723 mL | |
| 15 mM | 0.0873 mL | 0.4363 mL | 0.8726 mL | 2.1815 mL | |
| 20 mM | 0.0654 mL | 0.3272 mL | 0.6545 mL | 1.6361 mL | |
| 25 mM | 0.0524 mL | 0.2618 mL | 0.5236 mL | 1.3089 mL | |
| 30 mM | 0.0436 mL | 0.2182 mL | 0.4363 mL | 1.0908 mL | |
| 40 mM | 0.0327 mL | 0.1636 mL | 0.3272 mL | 0.8181 mL | |
| 50 mM | 0.0262 mL | 0.1309 mL | 0.2618 mL | 0.6545 mL |
Miriplatin Related Classifications
HY-16325A Related Classifications
Powered by Bioz