1. Protein Tyrosine Kinase/RTK
  2. Btk
  3. Tirabrutinib hydrochloride

Tirabrutinib hydrochloride (Synonyms: ONO-4059 (hydrochloride); GS-4059 (hydrochloride))

Cat. No.: HY-15771A Purity: 98.74%
Handling Instructions

Tirabrutinib (ONO-4059) hydrochloride is a selective and novel inhibitor of BTK with IC50 2.2 nm, Tirabrutinib binds to BTK within B cells, thereby preventing B-cell receptor signaling and impeding B-cell development.

For research use only. We do not sell to patients.

Tirabrutinib hydrochloride Chemical Structure

Tirabrutinib hydrochloride Chemical Structure

CAS No. : 1439901-97-9

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 121 In-stock
Estimated Time of Arrival: December 31
5 mg USD 110 In-stock
Estimated Time of Arrival: December 31
10 mg USD 180 In-stock
Estimated Time of Arrival: December 31
25 mg USD 350 In-stock
Estimated Time of Arrival: December 31
50 mg USD 550 In-stock
Estimated Time of Arrival: December 31
100 mg USD 850 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Description

Tirabrutinib (ONO-4059) hydrochloride is a selective and novel inhibitor of BTK with IC50 2.2 nm, Tirabrutinib binds to BTK within B cells, thereby preventing B-cell receptor signaling and impeding B-cell development.

IC50 & Target

IC50: 2.2 nM (BTK)[1].

Clinical Trial
Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
Molecular Weight

490.94

Formula

C₂₅H₂₃ClN₆O₃

CAS No.

1439901-97-9

SMILES

O=C1N(C2=CC=C(OC3=CC=CC=C3)C=C2)C4=C(N)N=CN=C4N1[[email protected]]5CN(C(C#CC)=O)CC5.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere

Purity: 98.74%

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Tirabrutinib hydrochloride
Cat. No.:
HY-15771A
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Tirabrutinib hydrochloride

Cat. No.: HY-15771A