Octopamine
Based on 5 publication(s) in Google Scholar
Octopamine is a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates. Octopamine can stimulate alpha2-adrenoceptors (ARs) in Chinese hamster ovary cells transfected with human alpha2-ARs. Octopamine increased glycogenolysis, glycolysis, oxygen uptake, gluconeogenesis and the portal perfusion pressure.
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- CAS No.: 104-14-3
- Formula: C8H11NO2
- Molecular Weight:153.18
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Octopamine
MoreAll Adrenergic Receptor Isoforms
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
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Human Endogenous Metabolite |
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Cell Line
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Type | Value | Description | References |
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| HEK293 | EC50 |
24 nM
Compound: octopamine
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Activity at SER3 receptor expressed in HEK293 cells assessed as increase in calcium by calcium imaging assay
Activity at SER3 receptor expressed in HEK293 cells assessed as increase in calcium by calcium imaging assay
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[PMID: 18033297] |
| Vero C1008 | IC50 |
>2.0 × 105M
Compound: COVC-0677843195
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Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging
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10.6019/CHEMBL4651402 |
Chemical Information
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CAS No. 104-14-3
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Appearance Solid
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Molecular Weight 153.18
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Formula C8H11NO2
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Color White to off-white
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SMILES
OC(C1=CC=C(O)C=C1)CN
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (5)
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Journal Impact Factor
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Most Recent
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Cell Res
Light sensing enhances thermotolerance and competitive fitness via serotonergic signaling in an eyeless organism. [Abstract]2026 Apr;36(4):286-299. PMID: 41764323 -
Nat Commun
2025 Dec 18;16(1):11196. PMID: 41413037 -
Insect Mol Biol
2022 Oct;31(5):647-658. PMID: 35652818 -
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Purity & Documentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Roeder T. Octopamine in invertebrates. Prog Neurobiol. 1999;59(5):533-561. [Content Brief]
[2]. Farooqui T. Octopamine-mediated neuromodulation of insect senses. Neurochem Res. 2007;32(9):1511-1529. [Content Brief]
[3]. Axelrod J, et al. Octopamine. Nature. 1977;265(5594):501-504. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Octopamine Related Classifications
HY-B0528 Related Classifications
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