104-14-3
Chemical Structure
Octopamine
Synonym(s): (±)-p-Octopamine
- CAS No.: 104-14-3
- Formula:C8H11NO2
- Molecular Weight:153.18
IUPAC Name: 4-(2-amino-1-hydroxyethyl)phenol
InChIKey: QHGUCRYDKWKLMG-UHFFFAOYSA-N
SMILES: OC(C1=CC=C(O)C=C1)CN
Biological Activity: Octopamine ((±)-p-Octopamine) is an orally active neurotransmitter and neuromodulator that can cross the blood-brain barrier. Octopamine activates octopamine receptors (octopamine receptor), G protein-coupled/Gαs-coupled receptors (G protein-coupled/Gαs-coupled receptor), adenylyl cyclase (adenylyl cyclase)/cAMP, calcium, and hyperpolarizing conductance increases. Octopamine can be used in research on various neurological diseases, metabolic diseases, and cardiovascular and cerebrovascular diseases[1][2][3][4].
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Octopamine | Octopamine ((±)-p-Octopamine) is an orally active neurotransmitter and neuromodulator that can cross the blood-brain barrier. Octopamine activates octopamine receptors (octopamine receptor), G protein-coupled/Gαs-coupled receptors (G protein-coupled/Gαs-coupled receptor), adenylyl cyclase (adenylyl cyclase)/cAMP, calcium, and hyperpolarizing conductance increases. Octopamine can be used in research on various neurological diseases, metabolic diseases, and cardiovascular and cerebrovascular diseases. | |||||||||||||||||||||
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Octopamine-d3 | 99.52% | Octopamine-d3 ((±)-p-Octopamine-d3) is the deuterated-labeled Octopamine (HY-B0528). Octopamine ((±)-p-Octopamine) is an orally active neurotransmitter and neuromodulator that can cross the blood-brain barrier. Octopamine activates octopamine receptors (octopamine receptor), G protein-coupled/Gαs-coupled receptors (G protein-coupled/Gαs-coupled receptor), adenylyl cyclase (adenylyl cyclase)/cAMP, calcium, and hyperpolarizing conductance increases. Octopamine can be used in research on various neurological diseases, metabolic diseases, and cardiovascular and cerebrovascular diseases. | ||||||||||||||||||||
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References
- [1]. Axelrod J, et al. Octopamine. Nature. 1977 Feb 10;265(5594):501-4. [Content Brief]
- [2]. Kaya-Zeeb S, et al. Octopamine drives honeybee thermogenesis. eLife. 2022 Mar 15;11:e74334.
- [3]. Farooqui T, et al. Octopamine-mediated neuromodulation of insect senses. Neurochemical research. 2007 Sep;32(9):1511-29. [Content Brief]
- [4]. Selcho M, et al. Linking physiological processes and feeding behaviors by octopamine. Current opinion in insect science. 2019 Dec;36:125-130.
