Sultopride hydrochloride
Based on 1 publication(s) in Google Scholar
Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist of dopamine D2 receptor.
For research use only. We do not sell to patients.
- Purity: 99.92%
- CAS No.: 23694-17-9
- Formula: C17H27ClN2O4S
- Molecular Weight:390.93
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocol
- Purity & Documentation
- References
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Publications Citing Use of MedChemExpress (MCE) Sultopride hydrochloride
MoreAll Dopamine Receptor Isoforms
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Biological Activity
Dopamine D2 receptor[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 23694-17-9
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Appearance Solid
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Molecular Weight 390.93
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Formula C17H27ClN2O4S
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Color White to off-white
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SMILES
O=C(NCC1N(CC)CCC1)C2=CC(S(=O)(CC)=O)=CC=C2OC.Cl
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Synonyms
LIN-1418 hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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Acta Pharmacol Sin
Isosibiricin inhibits microglial activation by targeting the dopamine D1/D2 receptor-dependent NLRP3/caspase-1 inflammasome pathway. [Abstract]2020 Feb;41(2):173-180. PMID: 31506572
Solvent & Solubility
H2O : 50 mg/mL (127.90 mM; Need ultrasonic)
DMSO : 50 mg/mL (127.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 140 mg/mL (358.12 mM); Clear solution; Need ultrasonic
Protocol
Thirty-six male Sprague-Dawley rats weighing 180 to 220 g are used in this study. The rats are divided into three groups of 6 each. One group is intraperitoneally injected with Sultopride hydrochloride (100 mg/kg body weight), the second group with sulphide (100 mg/kg body weight), and the third group with normal saline. One hundred minutes after the initial treatments, apomorphine (0.1 mg/kg body weight, dissolved in saline ad libitum) is administered subcutaneously to the three groups, and 20 minutes later the rats are sacrificed. The third group serves as controls[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 2.5580 mL | 12.7900 mL | 25.5800 mL | 63.9501 mL |
| 5 mM | 0.5116 mL | 2.5580 mL | 5.1160 mL | 12.7900 mL | |
| 10 mM | 0.2558 mL | 1.2790 mL | 2.5580 mL | 6.3950 mL | |
| 15 mM | 0.1705 mL | 0.8527 mL | 1.7053 mL | 4.2633 mL | |
| 20 mM | 0.1279 mL | 0.6395 mL | 1.2790 mL | 3.1975 mL | |
| 25 mM | 0.1023 mL | 0.5116 mL | 1.0232 mL | 2.5580 mL | |
| 30 mM | 0.0853 mL | 0.4263 mL | 0.8527 mL | 2.1317 mL | |
| 40 mM | 0.0640 mL | 0.3198 mL | 0.6395 mL | 1.5988 mL | |
| 50 mM | 0.0512 mL | 0.2558 mL | 0.5116 mL | 1.2790 mL | |
| 60 mM | 0.0426 mL | 0.2132 mL | 0.4263 mL | 1.0658 mL | |
| 80 mM | 0.0320 mL | 0.1599 mL | 0.3198 mL | 0.7994 mL | |
| 100 mM | 0.0256 mL | 0.1279 mL | 0.2558 mL | 0.6395 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Sultopride hydrochloride Related Classifications
HY-42849A Related Classifications
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