2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Aminopeptidase
  5. Aminopeptidase Substrate

Aminopeptidase Substrate

Aminopeptidase Isoform Comparison

Aminopeptidase Substrates (10):

Cat. No. Product Name Effect Purity
  • HY-137528
    H-Glu(4MβNA)-OH
    		Substrate 99.0%
    H-Glu(4MβNA)-OH is a substrate of aminopeptidases (APs).
  • HY-106154
    DTS-201
    		Substrate
    DTS-201 (CPI-0004) is a peptidic prodrug of Doxorubicin (HY-15142A). DTS-201, comprising the tetrapeptide portion, is cleaved by endopeptidases in the tumor environment to produce metabolites that subsequently enter the cell and are converted to active Doxorubicin. DTS-201 shows antitumoral efficacy in tumor xenograft models of prostate, breast, and lung cancer.
  • HY-W794670
    H-Ala-Pro-Ala-OH
    		Substrate
    H-Ala-Pro-Ala-OH, tripeptide, is a substrate for Escherichia coli PepP (Xaa-Pro aminopeptidase). H-Ala-Pro-Ala-OH acts as a nitrogen source for wild-type Escherichia coli.
  • HY-137946
    L-Leucine 4-methoxy-β-naphthylamide hydrochloride
    		Substrate
    L-Leucine 4-methoxy-β-naphthylamide hydrochloride is an aminopeptidase M and leucine aminopeptidase substrate.
  • HY-137842
    L-Alanine-2-naphthylamide
    		Substrate
    L-Alanine-2-naphthylamide (Alanine β-naphthylamide) is an Aminopeptidase (E.C. 3.4.11.) substrate and detection reagent. L-Alanine-2-naphthylamide detects the functional activity of aminopeptidase in the intestine of larval whitefish (Coregonus lavaretus). L-Alanine-2-naphthylamide serves as an initiator in the N-carboxyanhydride (NCA) method for synthesizing poly (β-benzyl-L-aspartate) polymers with a terminal 2-naphthyl energy donor group.
  • HY-W286423
    L-Pyroglutamic acid 7-amido-4-methylcoumarin
    		Substrate
    L-Pyroglutamic acid 7-amido-4-methylcoumarin is a fluorogenic substrate for pyroglutamate aminopeptidase 1 (PGP-1).
  • HY-P10759
    DTS-201 sodium
    		Substrate
    DTS-201 sodium (CPI-0004Na) is a peptidic prodrug of Doxorubicin (HY-15142A). DTS-201, comprising the tetrapeptide portion, is cleaved by endopeptidases in the tumor environment to produce metabolites that subsequently enter the cell and are converted to active Doxorubicin. DTS-201 shows antitumoral efficacy in tumor xenograft models of prostate, breast, and lung cancer.
  • HY-D3191
    L&M-D-MR
    		Substrate
    L&M-D-MR is a highly specific fluorescent "AND" logic probe with response moieties for leucine aminopeptidase (LAP) and monoamine oxidase (MAO). The coexistence of both LAP and MAO is required for L&M-D-MR to trigger intramolecular cyclization, release fluorophores and activate fluorescence. In the presence of only a single enzyme, L&M-D-MR generates only an extremely weak signal. L&M-D-MR enables bioimaging in living cells and mouse models, and can effectively distinguish different subtypes of liver diseases via blood samples or test strips. L&M-D-MR is widely used in studies related to liver cirrhosis, hepatitis B and drug-induced liver injury.
  • HY-165312
    Lysine-2-naphthylamide
    		Substrate
    Lysine-2-naphthylamide is a substrate of dipeptidylaminopeptidase.
  • HY-P2648
    Suc-Ala-Ala-Pro-Leu-pNA
    		Substrate 99.81%
    Suc-Ala-Ala-Pro-Leu-pNA (N-Succinyl-AAPL-p-nitroanilide) is a tripeptidyl p-nitroanilide substrate that can be catalytically hydrolyzed by acyl amidase-like leucine aminopeptidase in seminal plasma. Amastatin (HY-129298) and Actinonin (HY-113952) exert potent inhibitory effects on this hydrolytic activity. Suc-Ala-Ala-Pro-Leu-pNA can be used for the research of diseases such as azoospermia.