Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
All Product Categories
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Drug Intermediate Related Products (4595)
Related Products (4595)
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m-Tolylacetic acid (Standard)
0 ImagesSynonyms: 3-Methylbenzeneacetic acid (Standard)m-Tolylacetic acid (3-Methylbenzeneacetic acid) (Standard) is the analytical standard of m-Tolylacetic acid (HY-W053507). This product is intended for research and analytical applications. m-Tolylacetic acid is a hydroaromatic dicarboxylic acids excreted in the urine as metabolite of tolueneacetic acid. m-Tolylacetic acid can be used for drug intermediate for synthesising more complex molecules.
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POLRMT-IN-3
0 ImagesCat. No.: HY-181071POLRMT-IN-3 is a photosensitive inhibitor of mitochondrial RNA polymerase (POLRMT). POLRMT-IN-3 is biologically inactive in the dark but rapidly releases the active parent compound LJ03 upon illumination with 405 nm light, enabling spatiotemporally precise inhibition of POLRMT. POLRMT-IN-3 exhibits antitumor activity and can be used in research on tumors such as pancreatic cancer and ovarian cancer.
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Cyclosporin impurity 2
0 ImagesCat. No.: HY-W793067CAS No.: 138957-23-0Synonyms: Acetoxy cyclosporin A acetateCyclosporin impurity 2 (Acetoxy cyclosporin A acetate) is an impurity of Cyclosporin.
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XL388-C2-amide-PEG9-NH2 TFA
0 ImagesCat. No.: HY-139085BXL388-C2-amide-PEG9-NH2 TFA is an intermediate used in the synthesis of C26-linked Rapamycin analog.
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7-Aminodeacetoxycephalosporanic acid (Standard)
0 ImagesCat. No.: HY-W014217RCAS No.: 22252-43-3Synonyms: 7-ADCA (Standard)7-Aminodeacetoxycephalosporanic acid (Standard) is the analytical standard of 7-Aminodeacetoxycephalosporanic acid. This product is intended for research and analytical applications. 7-Aminodeacetoxycephalosporanic acid (7-ADCA) is a key intermediate in the synthesis of cephalosporins.
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GA44
0 ImagesCat. No.: HY-W746957CAS No.: 36434-15-8GA44 is a C20-gibberellin and is an intermediate in the early 13-hydroxylation pathway.
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BMS-135-L-Lys dihydrochloride
0 ImagesCat. No.: HY-184414BBMS-135-L-Lys dihydrochloride is a dual-cation prodrug derived from CK2 inhibitor BMS-135 (HY-181022) through esterification with L-lysine using a secondary alcohol. BMS-135-L-Lys dihydrochloride achieves enhanced solubility by maintaining protonation of the ε-amino group of the Lys side chain at intestinal pH. BMS-135-L-Lys dihydrochloride is released in situ by intestinal wall esterase from the parent drug, significantly increasing the oral bioavailability of the parent drug and overcoming the non-linear pharmacokinetic problem when the dose of the parent drug is increased. BMS-135-L-Lys dihydrochloride can be used in related research on colon cancer and lung cancer.
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3,4,5-Trimethoxybenzoic acid-d3
0 ImagesCat. No.: HY-Y0084SCAS No.: 84759-05-7Synonyms: Eudesmic acid-d3; Trimethylgallic acid-d33,4,5-Trimethoxybenzoic acid-d3 is the deuterium labeled 3,4,5-Trimethoxybenzoic acid[1]. 3,4,5-Trimethoxybenzoic acid (Eudesmic acid;Trimethylgallic Acid) is a benzoic acid derivative. A building block in medicine and organic synthesis. 3,4,5-Trimethoxybenzoic acid exhibits antibacterial activity against S. aureus with MIC of 0.97 μg/mL.
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Acorbine
0 ImagesCat. No.: HY-P12115CAS No.: 860314-33-6Acorbine is an orally active, hepatoprotective tripeptide present in the brackish-water bivalve Corbicula japonica. Hydrolysis of Acorbine yields free β-alanine and ornithine, which mediate the host defense system of Corbicula japonica in response to biological stress and changes in growth conditions. Acorbine inhibits ethanol-induced hepatocyte death and liver injury. Acorbine can be used in studies related to liver diseases.
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PNU 101850
0 ImagesCat. No.: HY-105373CAS No.: 852336-59-5PNU 101850 is an Eperezolid (HY-10393) ester prodrug. PNU 101850 acquires antibacterial activity after conversion to the parent drug Eperezolid.
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DL-Cystathionine dihydrochloride
0 ImagesCat. No.: HY-W009749BDL-Cystathionine dihydrochloride is a mixture of 4 isomers of cystathionine and allocystathionine. DL-Cystathionine dihydrochloride also is an intermediate in the biosynthesis of amino acid cysteine. DL-Cystathionine dihydrochloride serves as a standard for quantifying tissue cystathionine.
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Scrophuloside A
0 ImagesCat. No.: HY-N19942CAS No.: 886061-50-3Scrophuloside A is a phenylpropanoid glycoside identified from the rhizome of Neopicrorhiza scrophulariiflora. Scrophuloside A induces cytotoxicity in leukemia cells with a IC50 of 0.58 μg/mL. Scrophuloside A is applicable to leukemia-related research.
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H-Pro-His-OH
0 ImagesCat. No.: HY-W716776CAS No.: 92027-43-5H-Pro-His-OH is a commonly used amino acid building block in biochemistry and peptide synthesis.
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GalNA-PEG6-azido
0 ImagesCat. No.: HY-184771CAS No.: 2766875-91-4GalNA-PEG6-azido (P192 Compound 11) is a compound derived from N-acetylgalactosamine, bearing a PEG6 linker arm and an azido group, and serves as a drug linker.
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Fumiquinazoline A
0 ImagesCat. No.: HY-N19916CAS No.: 140715-85-1Fumiquinazoline A is a peptidyl quinazolinone indole alkaloid isolated from Aspergillus fumigatus, with antifungal activity. Fumiquinazoline A serves as a substrate for the flavoenzyme Af12070 and FAD-dependent amide oxidase Af12070, which oxidizes it into the seven-membered spiroaminal Fumiquinazoline C. Fumiquinazoline A is applicable to studies related to fungal infections.
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Cyclopropylmethyl bromide-d3
0 ImagesCat. No.: HY-Y1100S1CAS No.: 1219799-17-3Cyclopropylmethyl bromide-d3 is the deuterium labeled Cyclopropylmethyl bromide (HY-Y1100). Cyclopropylmethyl bromide is an intermediate. Cyclopropylmethyl bromide can be used in the preparation of Firocoxib (HY-14670). Firocoxib (ML 1785713) is a potent, selective, orally active COX-2 inhibitor.
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D-Lyxose-13C-2
0 ImagesCat. No.: HY-128753S3CAS No.: 70849-22-8D-Lyxose-13C-2 is the 13C labeled D-Lyxose. D-Lyxose is an endogenous metabolite. D-Lyxose is a rare pentose sugar with significant potential for drug synthesis. D-Lyxose can be used as a starting material for anti-tumor drugs such as alpha galactose ceramide immunostimulants. D-Lyxose can be used as a precursor for L-nucleoside analogs for the development of antiviral drugs. D-Lyxose can be used as a synthetic intermediate for other rare sugars such as L-ribose.
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Licoagrocarpin
0 ImagesCat. No.: HY-186188CAS No.: 202815-29-0
