Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Produits associés (11058)
Produits associés (11058)
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Ozanimod-d6
0 ImagesCat. No.: HY-12288SSynonyms: RPC-1063-d6Ozanimod-d6 (RPC-1063-d6) is the deuterium labeled Ozanimod (HY-12288). Ozanimod (RPC-1063) is a CNS-penetrant sphingosine 1-phosphate (S1P) receptor modulator that binds with high affinity selectively to S1P receptor subtypes 1 (S1P1) and 5 (S1P5). Ozanimod has modulate effect for hS1P1 and hS1P5 receptor with EC50s of 1.03 nM and 8.6 nM, respectively. Ozanimod can be used for the research of relapsing multiple sclerosis (MS).
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Metopimazine acid-d6 (hydrochloride)
0 ImagesCat. No.: HY-143994SMetopimazine-d6 hydrochloride is the deuterium labeled Metopimazine (HY-116578). Metopimazine (EXP999; RP9965) is a phenothiazine, orally available, selective dopamine D2 receptor antagonist that does not penetrate the blood-brain barrier. Metopimazine blocks dopamine D2 receptors in the chemoreceptor trigger zone and the periphery, thereby inhibiting nausea and vomiting. Metopimazine is indicated for chemotherapy-induced nausea and vomiting, and has low central side effects due to its poor brain penetration. The use of metopimazine in acute gastroenteritis may have potential risks.
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Nafronyl-d4 oxalate
0 ImagesCat. No.: HY-126568S1Nafronyl-d4 (oxalate) is deuterium labeled Naftidrofuryl.
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Propane-1,2,3-triyl tripalmitate-d27
0 ImagesCat. No.: HY-W013061S7CAS No.: 1219804-91-7Propane-1,2,3-triyl tripalmitate-d27 is the deuterium labeled Propane-1,2,3-triyl tripalmitate (HY-W013061). Propane-1,2,3-triyl tripalmitate is a saturated fat. Propane-1,2,3-triyl tripalmitate enhances the lymphatic transport of Glycerol tristearate (HY-127035).
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Levoketoconazole-d3
0 ImagesCat. No.: HY-B0105BSCAS No.: 1217766-70-5Synonyms: (-)-Ketoconazole-d3; (-)-Ketoconazol-d3; (-)-R 41400-d3(-)-Ketoconazole-d3 is deuterium labeled (-)-Ketoconazole. (-)-Ketoconazole ((-)-R 41400) is one of the enantiomer of Ketoconazole. Ketoconazole is a racemic mixture of two enantiomers, levoketoconazole ((2S,4R)-(−)-ketoconazole) and dextroketoconazole ((2R,4S)-(+)-ketoconazole).
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Odanacatib-d4
0 ImagesCat. No.: HY-10042SSynonyms: MK-0822-d4Odanacatib-d4 is the deuterium labeled Odanacatib (HY-10042). Odanacatib is a potent and selective inhibitor of cathepsin K, with an IC50 of 0.2 nM for human cathepsin K.
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Nefopam-d4 hydrochloride
0 ImagesCat. No.: HY-B1057S1CAS No.: 2747915-60-0Synonyms: Fenazoxine-d4 hydrochlorideNefopam-d4 (hydrochloride) is deuterium labeled Nefopam (hydrochloride). Nefopam hydrochloride (Fenazoxine hydrochloride) is a centrally-acting but non-opioid analgesic drug, for the relief of moderate to severe pain. Nefopam hydrochloride targets β-catenin protein level in mesenchymal cells in-vitro and in-vivo.
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trans-3'-Hydroxy Cotinine-d3 Acetate
0 ImagesCat. No.: HY-W749366CAS No.: 2714418-11-6trans-3'-Hydroxy Cotinine-d3 Acetate is the deuterium labeled trans-3'-Hydroxy Cotinine Acetate (HY-W739934).
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Dibenzo[a,h]acridine-d6
![Dibenzo[a,h]acridine-d6](https://file.medchemexpress.com/product_pic/hy-w703411.gif "Click to View Dibenzo[a,h]acridine-d6 Product Detail")
0 ImagesCat. No.: HY-W703411CAS No.: 1795031-62-7Dibenzo[a,h]acridine-d6 is the deuterium labeled Dibenz[a,h]acridine (HY-W762000).
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Midostaurin-13C6
0 ImagesCat. No.: HY-W751179Synonyms: PKC412-13C6; CGP 41251-13C6Midostaurin-13C6 (PKC412-13C6) is the 13C-labeled Midostaurin (HY-10230). Midostaurin (PKC412; CGP 41251) is an orally active, reversible multi-targeted protein kinase inhibitor. Midostaurin inhibits PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50s ranging from 22-500 nM. Midostaurin also upregulates endothelial nitric oxide synthase (eNOS) gene expression. Midostaurin shows powerful anticancer effects.
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DL-Lysine-13C6,15N2 hydrochloride
0 ImagesCat. No.: HY-B2236S2Synonyms: (±)-2,6-Diaminocaproic acid-13C6,15N2 hydrochloride
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Densil P-d6
0 ImagesCat. No.: HY-W770382Synonyms: Dithio-2,2'-bis(N-methylbenzamide)-d6Densil P-d6 (Dithio-2,2'-bis(N-methylbenzamide)-d6) is the deuterium labeled 2,2'-Disulfanediylbis(N-methylbenzamide) (HY-W250896).
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2-Chloro-5-methylpyrimidin-4-amine-15N2,13C
0 ImagesCat. No.: HY-W747218CAS No.: 2724728-73-6Synonyms: 4-Amino-2-chloro-5-methylpyrimidine-15N2,13C; CHLOROAMINOMETHYLPYRIMIDINE-15N2,13C2-Chloro-5-methylpyrimidin-4-amine-15N2,13C (4-Amino-2-chloro-5-methylpyrimidine-15N2,13C) is the 13C- and 15N-labeled 2-Chloro-5-methylpyrimidin-4-amine (HY-W002966).
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2′-Deoxyguanosine 5′-monophosphate-13C10 dilithium
0 ImagesCat. No.: HY-W393970S2Synonyms: 5'-Deoxyguanylic acid-13C10 dilithium2′-Deoxyguanosine 5′-monophosphate-13C10 (5'-Deoxyguanylic acid-13C10) dilithium is 13C-labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).
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Ivabradine-d6
0 ImagesCat. No.: HY-B0162SCAS No.: 2070009-62-8Ivabradine-d6 is the deuterium labeled Ivabradine. Ivabradine is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). Ivabradine reduces dose-dependently heart rate without modification of blood pressure. Ivabradine shows anticonvulsant, anti-ischaemic and anti-anginal activity.
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2,4-Di-tert-butylphenol-d10
0 ImagesCat. No.: HY-W749499CAS No.: 1577233-50-12,4-Di-tert-butylphenol-d10 is the deuterium labeled 2,4-Di-tert-butylphenol.
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Lofexidine-d4
0 ImagesCat. No.: HY-B1052S1CAS No.: 78302-26-8Synonyms: Baq-168 free base-d4; MDL-14042 free base-d4Lofexidine-d4 (Baq-168 free base-d4) is deuterium labeled Lofexidine (HY-B1052A). Lofexidine (Baq-168 free base) is an orally active agonist of the imidazoline I1 receptor (imidazoline I1 receptor) (Ki: 1.9 nM) and α2-adrenergic receptor (α2-adrenergic receptor). Lofexidine binds to the α2A-adrenergic receptor, reduces sympathetic outflow, lowers blood pressure, and exhibits vasoconstrictive effects. Lofexidine regulates the expression of c-fos and alleviates opioid withdrawal symptoms. Lofexidine is applicable to research on opioid addiction and withdrawal.
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Ac-DL-Ala-OH-d4
0 ImagesCat. No.: HY-W010389S2Ac-DL-Ala-OH-d4 is the deuterium labeled Ac-DL-Ala-OH.
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N-Methyl-N-phenylnitrous amide-d5
0 ImagesCat. No.: HY-W725046CAS No.: 1821341-18-7N-Methyl-N-phenylnitrous amide-d5 is the deuterium labeled N-Methyl-N-phenylnitrous amide (HY-W015813).
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N,N-Dimethyltryptamine N-oxide-d6
0 ImagesCat. No.: HY-W753452N,N-Dimethyltryptamine N-oxide-d6 is the deuterium labeled N,N-Dimethyltryptamine N-oxide (HY-W576312). N,N-Dimethyltryptamine N-oxide is a metabolite of N,N-Dimethyltryptamine.
