Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1037)
Related Products (1037)
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DSPE-PEG10000-CHO
0 ImagesCat. No.: HY-176509DDSPE-PEG10000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG10000-CHO can be used for drug delivery.
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Linoleyl methane sulfonate
0 ImagesCat. No.: HY-142987CAS No.: 51154-39-3Linoleyl methane sulfonate is a selective lipid-based vehicle for use in drug delivery systems.
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DSPE-PEG5000-Mal-Cys-KTLLPTP
0 ImagesCat. No.: HY-172270DDSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors.
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Cholesterol hexanoate
0 ImagesCat. No.: HY-W127331CAS No.: 1062-96-0Cholesterol hexanoate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and caproic acid. Cholesterol hexanoate has several applications in the pharmaceutical industry, particularly as a bioactive compound with potential research potential for improving a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.
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DSPE-PEG3400-VHPKQHRGGSKGC
0 ImagesCat. No.: HY-182101BDSPE-PEG3400-VHPKQHRGGSKGC is a targeted modified phospholipid-polyethylene glycol conjugate covalently coupled to DSPE, PEG, and the vascular-targeting peptide VHPKQHRGGSKGC. DSPE-PEG3400-VHPKQHRGGSKGC can be used for research on tumor vascular imaging and vascular-targeted drug delivery.
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DSPE-PEG3400-PP1
0 ImagesCat. No.: HY-172708ADSPE-PEG3400-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG3400-PP1 can be used for drug delivery.
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1-Palmitoyl-sn-glycerol 3-phosphate-d9
0 ImagesCat. No.: HY-126967ASCAS No.: 2830282-77-2Synonyms: 1-P-GPA-d91-Palmitoyl-sn-glycerol 3-phosphate-d9 (1-P-GPA-d9) is the d9 labeled 1-Palmitoyl-sn-glycerol 3-phosphate (HY-126967A). 1-Palmitoyl-sn-glycerol 3-phosphate (1-P-GPA) is a phospholipid and lipid membrane precursor. 1-Palmitoyl-sn-glycerol 3-phosphate integrates into POPC liposomes, causing significant changes in membrane curvature. 1-Palmitoyl-sn-glycerol 3-phosphate induces platelet aggregation, but its activity is 30-fold lower than that of 1-hexadecyl-sn-glyceryl-3-phosphate.
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DSPE-PEG-Cyanur ammonium
0 ImagesCat. No.: HY-144011CAS No.: 1246304-74-4DSPE-PEG-Cyanur ammonium is a PEG derivative containing cyanur functional group. DSPE-PEG-Cyanur ammonium can be used for PEGylation of protein under mild basic conditions. DSPE-PEG-Cyanur ammonium can be used for nanostructured lipid carrier.
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DOIC
0 ImagesCat. No.: HY-142999CAS No.: 1292821-06-7DOIC is a cationic lipid that can be used for RNA vaccines.
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DSPE-PEG5000-MG1
0 ImagesCat. No.: HY-182096CDSPE-PEG5000-MG1 is a PEG compound which composed of DSPE and a MG1 peptide (HY-P11315). MG1 peptide is a M1 Microglia-targeting peptide. MG1 peptide can conjugate to anoparticles, crossing the BBB to precisely M1 microglia recognition and achieving controlled release and specific accumulation of drugs through intelligent molecular switching. DSPE-PEG5000-KTP can be used for drug delivery.
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DSPE-PEG1000-Mal-CLPLIPTHIISFS
0 ImagesCat. No.: HY-172499DSPE-PEG1000-Mal-CLPLIPTHIISFS is a PEG compound composed of DSPE and the liver cancer targeting peptide SP94 (HY-P11050A) (sequence SFSIIHTPILPL). SP94 exhibits specific binding to hepatocellular carcinoma (HCC) cells. DSPE-PEG1000-Mal-CLPLIPTHIISFS can be used to prepare lipid nanoparticles to form liver cancer-targeting nanocarriers.
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CP-LC-1422
0 ImagesCat. No.: HY-176027CP-LC-1422 is a homocysteine-derived ionizable amino lipid with high RNA delivery capability and can mediate high-level protein expression in vivo. CP-LC-1422 exhibits significant spleen targeting via intravenous injection in a lipid nanoparticle (LNP) formulation with no significant toxicity observed.
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MHAPC-Chol
0 ImagesCat. No.: HY-136869CAS No.: 1027801-74-6MHAPC-Chol, a cationic cholesterol, results in a high gene silencing effect via high cellular association. MHAPC-Chol delivers siRNA to the liver.
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DMPG
0 ImagesCat. No.: HY-177191CAS No.: 185463-22-3Synonyms: L-α-Dimyristoylphosphatidylglycerol; 1,2-Dimyristoyl-sn-glycero-3-phosphoglycerolDMPG (L-α-Dimyristoylphosphatidylglycerol; 1,2-Dimyristoyl-sn-glycero-3-phosphoglycerol) is a phospholipid that can be used for preparing formulations such as liposomes or gels. DMPG can be used in the research of drug delivery.
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DSPE-PEG3400-Mal-Cys-KTLLPTP
0 ImagesCat. No.: HY-172270CDSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors.
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C13-113-tetra-tail
0 ImagesCat. No.: HY-W440684CAS No.: 1381861-97-7C13-113-tetra tail is a cationic lipid-like compound containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a tertiary amine linker. C13-113-tetra tail can be formulated into a lipid nanoparticle (LNP).
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DSPE-PEG3400-K237
0 ImagesCat. No.: HY-172488ADSPE-PEG3400-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG3400-K237 can be used for drug delivery.
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Cholesterol (from plant)
0 ImagesCholesterol (from plant) is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol (from plant) plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins. Cholesterol (from plant) is also an endogenous estrogen-related receptor α (ERRα) agonist.
