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  4. MG1 peptide

MG1 peptide is an M1 microglia-targeting peptide with blood-brain barrier permeability. MG1 peptide can be used in studies related to ischemic stroke and cerebral ischemia-reperfusion injury.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

MG1 peptide

MG1 peptide Chemical Structure

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MG1 peptide Related Antibodies

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Description

MG1 peptide is an M1 microglia-targeting peptide with blood-brain barrier permeability. MG1 peptide can be used in studies related to ischemic stroke and cerebral ischemia-reperfusion injury[1][2].

In Vitro

MG1 peptide-modified engineered nanoerythrocytes can cross the in vitro blood-brain barrier, precisely target M1 microglia, drive the polarization of microglia toward the anti-inflammatory M2 phenotype, and alleviate neuroinflammation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

MG1 peptide Related Antibodies
Molecular Weight

985.06

Formula

C36H56N16O13S2
Appearance

Solid

Color

White to off-white

Sequence

Cys-His-His-Ser-Ser-Ser-Ala-Arg-Cys (Disulfide Bridge:Cys1-Cys9)
Sequence Shortening

CHHSSSARC (Disulfide Bridge:Cys1-Cys9)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (101.52 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0152 mL 5.0758 mL 10.1517 mL
5 mM 0.2030 mL 1.0152 mL 2.0303 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.0152 mL 5.0758 mL 10.1517 mL 25.3792 mL
5 mM 0.2030 mL 1.0152 mL 2.0303 mL 5.0758 mL
10 mM 0.1015 mL 0.5076 mL 1.0152 mL 2.5379 mL
15 mM 0.0677 mL 0.3384 mL 0.6768 mL 1.6919 mL
20 mM 0.0508 mL 0.2538 mL 0.5076 mL 1.2690 mL
25 mM 0.0406 mL 0.2030 mL 0.4061 mL 1.0152 mL
30 mM 0.0338 mL 0.1692 mL 0.3384 mL 0.8460 mL
40 mM 0.0254 mL 0.1269 mL 0.2538 mL 0.6345 mL
50 mM 0.0203 mL 0.1015 mL 0.2030 mL 0.5076 mL
60 mM 0.0169 mL 0.0846 mL 0.1692 mL 0.4230 mL
80 mM 0.0127 mL 0.0634 mL 0.1269 mL 0.3172 mL
100 mM 0.0102 mL 0.0508 mL 0.1015 mL 0.2538 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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MG1 peptide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MG1 peptideBiochemical Assay ReagentsM1 microglia-targeting peptideischemic strokecerebral ischemia-reperfusion injuryInhibitorinhibitorinhibit

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