MG1 peptide
Based on 1 Customer Validation
MG1 peptide is an M1 microglia-targeting peptide with blood-brain barrier permeability. MG1 peptide can be used in studies related to ischemic stroke and cerebral ischemia-reperfusion injury.
For research use only. We do not sell to patients.
- Purity: 99.23%
- Formula: C36H56N16O13S2
- Molecular Weight:985.06
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MG1 peptide-modified engineered nanoerythrocytes can cross the in vitro blood-brain barrier, precisely target M1 microglia, drive the polarization of microglia toward the anti-inflammatory M2 phenotype, and alleviate neuroinflammation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 985.06
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Formula C36H56N16O13S2
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Color White to off-white
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Sequence
Cys-His-His-Ser-Ser-Ser-Ala-Arg-Cys (Disulfide Bridge:Cys1-Cys9)
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Sequence Shortening
CHHSSSARC (Disulfide Bridge:Cys1-Cys9)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : ≥ 100 mg/mL (101.52 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (280 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Ren JX, et al. Emerging Targeted Delivery Strategies of Nanosystems for Ischemic Stroke Treatment. Int J Nanomedicine. 2025;20:8143-8171. Published 2025 Jun 24. [Content Brief]
[2]. Cheng Z, et al. Cascade-Type Microglial Pyroptosis Inhibitors for Enhanced Treatment of Cerebral Ischemia-Reperfusion Injury. ACS Nano. 2025;19(10):10529-10548. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.0152 mL | 5.0758 mL | 10.1517 mL | 25.3792 mL |
| 5 mM | 0.2030 mL | 1.0152 mL | 2.0303 mL | 5.0758 mL | |
| 10 mM | 0.1015 mL | 0.5076 mL | 1.0152 mL | 2.5379 mL | |
| 15 mM | 0.0677 mL | 0.3384 mL | 0.6768 mL | 1.6919 mL | |
| 20 mM | 0.0508 mL | 0.2538 mL | 0.5076 mL | 1.2690 mL | |
| 25 mM | 0.0406 mL | 0.2030 mL | 0.4061 mL | 1.0152 mL | |
| 30 mM | 0.0338 mL | 0.1692 mL | 0.3384 mL | 0.8460 mL | |
| 40 mM | 0.0254 mL | 0.1269 mL | 0.2538 mL | 0.6345 mL | |
| 50 mM | 0.0203 mL | 0.1015 mL | 0.2030 mL | 0.5076 mL | |
| 60 mM | 0.0169 mL | 0.0846 mL | 0.1692 mL | 0.4230 mL | |
| 80 mM | 0.0127 mL | 0.0634 mL | 0.1269 mL | 0.3172 mL | |
| 100 mM | 0.0102 mL | 0.0508 mL | 0.1015 mL | 0.2538 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
MG1 peptide Related Classifications
HY-P11315 Related Classifications
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