DSPE-PEG1000-Mal-CLPLIPTHIISFS
DSPE-PEG1000-Mal-CLPLIPTHIISFS is a PEG compound composed of DSPE and the liver cancer targeting peptide SP94 (HY-P11050A) (sequence SFSIIHTPILPL). SP94 exhibits specific binding to hepatocellular carcinoma (HCC) cells. DSPE-PEG1000-Mal-CLPLIPTHIISFS can be used to prepare lipid nanoparticles to form liver cancer-targeting nanocarriers.
For research use only. We do not sell to patients.
- Molecular Weight:1000 (Average)
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
DSPE, or distearate phosphatidylethanolamine, is a phospholipid molecule with excellent biocompatibility and membrane fusion capabilities.
PEG, or polyethylene glycol, is a commonly used polymer that can increase the stability and bioavailability of materials.
The SP94 peptide specifically recognizes liver cancer cell surface markers (such as GRP78 protein) and has no affinity for normal hepatocytes, achieving precise targeting.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 1000 (Average)
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SMILES
[Mal-CLPLIPTHIISFS]C(CCOCCOC(NCCOP(OC[C@](COC(CCCCCCCCCCCCCCCCC)=O)([H])OC(CCCCCCCCCCCCCCCCC)=O)(O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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