Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4595)
Related Products (4595)
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(2R,4S)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoate
![(2R,4S)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoate](https://file.medchemexpress.com/product_pic/hy-z0066.gif "Click to View (2R,4S)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoate Product Detail")
0 Images(2R,4S)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoate is a drug intermediate for synthesis of various active compounds.
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ε-Caprolactone
0 Imagesε-Caprolactone is a 7-membered cyclic ester identified in Rubus arcticus L, and it is also a versatile monomer. ε-Caprolactone serves as an intermediate to derive various functional polymer materials. ε-Caprolactone is applicable to relevant research in fields such as biomedicine and material synthesis.
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4,4'-Trimethylenedipyridine
0 ImagesCat. No.: HY-W034556CAS No.: 17252-51-64,4'-Trimethylenedipyridine is a drug intermediate for synthesis of various active compounds.
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3-Methyl-4-(pyridin-4-yl)aniline
0 ImagesCat. No.: HY-I0874CAS No.: 82160-27-83-Methyl-4-(pyridin-4-yl)aniline is a drug intermediate for synthesis of various active compounds.
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(2-Butyl-5-nitrobenzofuran-3-yl)(4-methoxyphenyl)methanone
0 Images(2-Butyl-5-nitrobenzofuran-3-yl)(4-methoxyphenyl)methanone is a drug intermediate for synthesis of various active compounds.
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1-(Pyrimidin-5-yl)ethan-1-ol
0 ImagesCat. No.: HY-W062571CAS No.: 79691-74-0Synonyms: α-Methyl-5-pyriMidineMethanol1-(Pyrimidin-5-yl)ethan-1-ol (α-Methyl-5-pyriMidineMethanol) is a drug intermediate for synthesis of various active compounds.
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Pentane-1,3,5-triol
0 ImagesCat. No.: HY-W358956CAS No.: 4328-94-3Pentane-1,3,5-triol is a drug intermediate for synthesis of various active compounds.
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Tosylate-DPA-714
0 ImagesTosylate-DPA-714 is a GMP-grade precursor for the radiosynthesis of DPA-714 (HY-122607). It crosses the blood-brain barrier and exhibits steroidogenic activity. DPA-714 is a specific ligand for the 18 kDa translocator protein (TSPO) with a Ki of 7.0 nM. Tosylate-DPA-714 is safe and does not bind to central benzodiazepine receptors (benzodiazepine receptor). As a radiolabeling precursor, Tosylate-DPA-714 reacts with 18F via nucleophilic aliphatic substitution to form 18F-DPA-714, enabling specific targeted binding to TSPO. 18F-DPA-714 accurately reflects the level of neuroinflammation mediated by microglial activation, and is used for PET molecular imaging of neurological diseases such as Alzheimer's disease and multiple sclerosis.
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3-((tert-Butoxycarbonyl)amino)-7-fluoro-8-((triisopropylsilyl)ethynyl)naphthalen-1-yl trifluoromethanesulfonate
0 Images3-((tert-Butoxycarbonyl)amino)-7-fluoro-8-((triisopropylsilyl)ethynyl)naphthalen-1-yl trifluoromethanesulfonate is a drug intermediate for synthesis of various active compounds.
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2-(2-Chloroethoxy)ethanol
0 Images2-(2-Chloroethoxy)ethanol (Diethylene glycol monochlorohydrin) is an unclassified residual solvent and known impurity, with an acceptance criterion of 0.10%.2-(2-Chloroethoxy)ethanol serves as a starting material in quetiapine synthesis.
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2-Chloro-1-(4-methoxy-1H-indol-3-yl)ethanone
0 Images2-Chloro-1-(4-methoxy-1H-indol-3-yl)ethanone is a drug intermediate for synthesis of various active compounds.
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Adipic acid dihydrazide
0 ImagesAdipic acid dihydrazide (Adipodihydrazide) is an antibacterial agent and crosslinking agent. Adipic acid dihydrazide can be used for the preparation of hydrogels. Adipic acid dihydrazide exhibits antibacterial activity against both Gram-positive and Gram-negative bacteria, such as Enterobacter aerogenes (MIC: 0.081 mg/mL) and Salmonella enterica (MIC: 0.99 mg/mL). Adipic acid dihydrazide is also an important intermediate that can be utilized in the synthesis of other active compounds.
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4-(4-Bromobenzyl)morpholine
0 Images4-(4-Bromobenzyl)morpholine is a drug intermediate for synthesis of various active compounds.
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Methyl 3-(2-((tert-butoxycarbonyl)amino)ethyl)benzoate
0 ImagesMethyl 3-(2-((tert-butoxycarbonyl)amino)ethyl)benzoate is a drug intermediate for synthesis of various active compounds.
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1-Boc-D-azetidine-2-carboxylic acid
0 Images1-Boc-D-azetidine-2-carboxylic acid is a non-protein-derived chiral amino acid building block, which is used for the synthesis of various active compounds.
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2-Amino-4-bromophenol
0 ImagesCat. No.: HY-W007625CAS No.: 40925-68-62-Amino-4-bromophenol is a drug synthesis intermediate that can be used to synthesize an inhibitor of soluble guanylate cyclase (sGC).
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4-Bromo-2-fluoropyridine
0 Images4-Bromo-2-fluoropyridine is a drug intermediate.
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(S)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde
0 ImagesCat. No.: HY-69348CAS No.: 102308-32-7(S)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde is a chiral compound. (S)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde is commonly used as a chiral intermediate in asymmetric synthesis and has important applications in the field of organic synthesis.
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SerBut
0 ImagesSerBut is a serine conjugated butyrate prodrug with oral activity. SerBut has anti-inflammatory activity.
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(R)-1-Boc-3-methyl-piperazine
0 Images(R)-1-Boc-3-methyl-piperazine (Compound I3-1) is a chemical intermediate. (R)-1-Boc-3-methyl-piperazine can be used for the preparation of Compound I3. Compound I3 exhibits anticancer activity against colorectal adenocarcinoma with BRCA2 gene deletion.
