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Abacavir hydroxyacetate 

Cat. No.: HY-106647 Purity: 98.29%
Handling Instructions

Abacavir hydroxyacetate is an orally active inhibitor of IL-20 and PRINS. Abacavir hydroxyacetate reduces proliferation rate of skin in psoriasis as an immune modulator. Abacavir hydroxyacetate can be used for the research of inflammatory skin problems.

For research use only. We do not sell to patients.

Abacavir hydroxyacetate Chemical Structure

Abacavir hydroxyacetate Chemical Structure

CAS No. : 1446418-48-9

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100 mg USD 1040 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Abacavir hydroxyacetate is an orally active inhibitor of IL-20 and PRINS. Abacavir hydroxyacetate reduces proliferation rate of skin in psoriasis as an immune modulator. Abacavir hydroxyacetate can be used for the research of inflammatory skin problems[1][2].

In Vivo

Abacavir hydroxyacetate (10-20 mg/kg; p.o. once) effectively controls psoriasis of mice[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 6 to 8-week-old male and female SCID mice with implantation of psoriatic tissue[2]
Dosage: 10 and 20 mg/kg
Administration: Oral gavage; 10-20 mg/kg once
Result: Decreased the concentration of PRINS and 1L-20, and reduced the lesion area of skin. Showed a better effect than methotrexate in controlling psoriasis.
Molecular Weight

344.37

Formula

C16H20N6O3

CAS No.
SMILES

OCC(OC[[email protected]](C=C1)C[[email protected]]1N2C3=NC(N)=NC(NC4CC4)=C3N=C2)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
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Product Name:
Abacavir hydroxyacetate
Cat. No.:
HY-106647
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