1. GPCR/G Protein
  2. LPL Receptor
  3. ASP6432

ASP6432 

Cat. No.: HY-120478
Handling Instructions

ASP6432 is a potent and selective type 1 lysophosphatidic acid receptor (LPA1) antagonist with IC50s of 11 nM and 30 nM for human LPA1 and rat LPA1, respectively.

For research use only. We do not sell to patients.

ASP6432 Chemical Structure

ASP6432 Chemical Structure

CAS No. : 1282549-08-9

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Description

ASP6432 is a potent and selective type 1 lysophosphatidic acid receptor (LPA1) antagonist with IC50s of 11 nM and 30 nM for human LPA1 and rat LPA1, respectively[1].

IC50 & Target

IC50: 11 nM (human LPA1), 30 nM (rat LPA1)[1]

In Vitro

ASP6432 inhibits the LPA-induced proliferation of human prostate stromal cells[1].

Molecular Weight

598.78

Formula

C₂₆H₃₁KN₄O₆S₂

CAS No.

1282549-08-9

SMILES

O=C(C1=CSC(CN(C(C2=CC(OC)=C(C)C(OC)=C2)=O)CCCC3=CC=CC=C3)=N1)[N-]S(=O)(NCC)=O.[K+]

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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ASP6432
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