Adenosine-15N5
Based on 1 Customer Validation
Adenosine-15N5 (Adenine riboside-15N5; D-Adenosine-15N5) is the 15N labled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.
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- Reinheit: 99.9%
- CAS. Nr.: 168566-57-2
- Formel: C10H1315N5O4
- Molecular Weight:272.21
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 168566-57-2
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Unlabeled Cas 58-61-7
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Appearance Solid
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Molecular Weight 272.21
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Formel C10H1315N5O4
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Color White to off-white
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SMILES
O[C@H]1[C@@H](O)[C@H]([15N]2C3=[15N]C=[15N]C([15NH2])=C3[15N]=C2)O[C@@H]1CO
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Synonyms
Adenine riboside-15N5; D-Adenosine-15N5
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 33.33 mg/mL (122.44 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Zhou XT, et al. Inhibition of autophagy enhances adenosine induced apoptosis in human hepatoblastoma HepG2 cells. Oncol Rep. 2019;41(2):829-838. [Content Brief]
[2]. Eltzschig HK. Adenosine: an old drug newly discovered. Anesthesiology. 2009;111(4):904-915. [Content Brief]
[3]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 3.6736 mL | 18.3682 mL | 36.7363 mL | 91.8409 mL |
| 5 mM | 0.7347 mL | 3.6736 mL | 7.3473 mL | 18.3682 mL | |
| 10 mM | 0.3674 mL | 1.8368 mL | 3.6736 mL | 9.1841 mL | |
| 15 mM | 0.2449 mL | 1.2245 mL | 2.4491 mL | 6.1227 mL | |
| 20 mM | 0.1837 mL | 0.9184 mL | 1.8368 mL | 4.5920 mL | |
| 25 mM | 0.1469 mL | 0.7347 mL | 1.4695 mL | 3.6736 mL | |
| 30 mM | 0.1225 mL | 0.6123 mL | 1.2245 mL | 3.0614 mL | |
| 40 mM | 0.0918 mL | 0.4592 mL | 0.9184 mL | 2.2960 mL | |
| 50 mM | 0.0735 mL | 0.3674 mL | 0.7347 mL | 1.8368 mL | |
| 60 mM | 0.0612 mL | 0.3061 mL | 0.6123 mL | 1.5307 mL | |
| 80 mM | 0.0459 mL | 0.2296 mL | 0.4592 mL | 1.1480 mL | |
| 100 mM | 0.0367 mL | 0.1837 mL | 0.3674 mL | 0.9184 mL |
Adenosine-15N5 Related Classifications
HY-B0228S11 Related Classifications
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