MK-8318
MK-8318 is a potent and selective CRTh2 receptor antagonist with a Ki of 5.0 nM.
For research use only. We do not sell to patients.
- CAS No.: 1416581-40-2
- Formula: C27H26F4N2O5
- Molecular Weight:534.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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DP 5.0 nM (Ki) |
β-arrestin 3.5 nM (IC50) |
cAMP 8.0 nM (IC50) |
CYP3A4 50 μM (IC50) |
CYP2C9 50 μM (IC50) |
CYP2D6 50 μM (IC50) |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1416581-40-2
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Molecular Weight 534.50
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Formula C27H26F4N2O5
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SMILES
FC1=CC=C(N(C(C2=CC=C(OC(F)(F)F)C=C2)=O)[C@@H](CCC3)[C@@H]3[C@H]4N(C(CCC(O)=O)=O)C5CC5)C4=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MK-8318 Related Classifications
HY-112604 Related Classifications
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