BET-IN-15
BET-IN-15 (compound 1) is a potent and orally active BET inhibitor with IC50 values of 0.64，0.25 nM for BRD4-BD1，BRD4-BD2，respectively. BET-IN-15 shows antiproliferative activity.
For research use only. We do not sell to patients.
- CAS No.: 2408994-22-7
- Formula: C21H18F2N4O3S
- Molecular Weight:444.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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BRD4-BD1 0.64 nM (IC50) |
BRD4-BD2 0.25 nM (IC50) |
BET-IN-15 (compound 1) (72 h) shows antiproliferative activity with IC50s of 3.14，1.56 nM for MV4-11，Kasumi-1 cellS，respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2408994-22-7
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Molecular Weight 444.45
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Formula C21H18F2N4O3S
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SMILES
O=C1C2=C(C(C3=C(OC4=CC=C(C=C4F)F)C=CC(N=S(C)(C)=O)=N3)=CN1C)C=CN2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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