p53 Activator 13
p53 Activator 13 (compound 11) is a 6mA methyltransferase CamA inhibitor and a p53 activator. p53 Activator 13 intercalates into CamA-bound DNA via the minor groove, causing a conformational shift that moves the catalytic domain away from the DNA and elicits DNA damage response via p53 activation. p53 Activator 13 can be utilized in cancer research.
For research use only. We do not sell to patients.
- Formula: C33H35N9O
- Molecular Weight:573.69
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA Methyltransferase Isoforms
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Biological Activity
Chemical Information
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Molecular Weight 573.69
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Formula C33H35N9O
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SMILES
O=C(NC1=CC(CN2CCN(C)CC2)=CC(NC3=NC(N)=NC(C)=C3)=C1)C4=CC=CC(NC5=CC=NC6=C5C=CC=C6)=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)