COX-2-IN-17
COX-2-IN-17 (compound 10) is a potent and BBB-penetrated COX-2 (cyclooxygenase-2) inhibitor, with an IC50 of 0.02 μM. COX-2-IN-17 shows anti-inflammatory and analgesic activities. COX-2-IN-17 attenuates hyperalgesia in the neurogenic phase as well as the inflammatory phase.
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- CAS No.: 2411390-10-6
- Formule: C20H23ClN6O2
- Masse moléculaire:414.89
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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COX-2 0.02 μM (IC50) |
COX-1 >10 μM (IC50) |
Chemical Information
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CAS No. 2411390-10-6
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Masse moléculaire 414.89
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Formule C20H23ClN6O2
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SMILES
N[C@@H](CC1=CN(C2=NC(Cl)=NC(N3CCCCC3)=N2)C4=CC=CC=C14)C(OC)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
COX-2-IN-17 Related Classifications
HY-147748 Related Classifications
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