2411390-10-6

COX-2-IN-17 Chemical Structure
2411390-10-6

Chemical Structure

COX-2-IN-17

  • CAS No.: 2411390-10-6
  • Formula:C20H23ClN6O2
  • Molecular Weight:414.89

IUPAC Name: methyl 1-(4-chloro-6-(piperidin-1-yl)-1,3,5-triazin-2-yl)-L-tryptophanate

InChIKey: FDJHAIWHVOSEBD-HNNXBMFYSA-N

SMILES: N[C@@H](CC1=CN(C2=NC(Cl)=NC(N3CCCCC3)=N2)C4=CC=CC=C14)C(OC)=O

Biological Activity: COX-2-IN-17 (compound 10) is a potent and BBB-penetrated COX-2 (cyclooxygenase-2) inhibitor, with an IC50 of 0.02 μM. COX-2-IN-17 shows anti-inflammatory and analgesic activities. COX-2-IN-17 attenuates hyperalgesia in the neurogenic phase as well as the inflammatory phase[1].

Cat. No. Product Name Purity Description Pricing
HY-147748
COX-2-IN-17 COX-2-IN-17 (compound 10) is a potent and BBB-penetrated COX-2 (cyclooxygenase-2) inhibitor, with an IC50 of 0.02 μM. COX-2-IN-17 shows anti-inflammatory and analgesic activities. COX-2-IN-17 attenuates hyperalgesia in the neurogenic phase as well as the inflammatory phase.
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