DR4485 hydrochloride
DR4485 (hydrochloride) is an orally active and selective 5-HT7 antagonist (pKi=8.14).
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- CAS No.: 402942-53-4
- Formule: C26H29Cl3N2O
- Masse moléculaire:491.88
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Voir tous les produits spécifiques à Isoform 5-HT Receptor
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Activité biologique
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5-HT7 Receptor |
5-HT7 Receptor 8.14 (pKi) |
Chemical Information
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CAS No. 402942-53-4
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Masse moléculaire 491.88
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Formule C26H29Cl3N2O
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SMILES
O=C1NC2=C3C1(CCCCN4CC=C(C5=CC=C(Cl)C=C5)CC4)CCCC3=C(Cl)C=C2.[H]Cl
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Kikuchi C, et al. New tetrahydrobenzindoles as potent and selective 5-HT(7) antagonists with increased In vitro metabolic stability. Bioorg Med Chem Lett. 2003;13(1):61-64. [Content Brief]
[2]. Meyer N, et al. Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death [published online ahead of print, 2021 Jan 19]. Autophagy. 2021;1-20. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DR4485 hydrochloride Related Classifications
HY-103126 Related Classifications
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