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Cat. No.: HY-179595

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GSK4394835A

GSK4394835A is a reversible covalent inhibitor of PDE3B with a pIC₅₀ of 6.2. GSK4394835A can be used for cardiovascular disease research.

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CAS No.: 3032458-06-0
Formule: C₂₇H₂₆BN₃O₆
Masse moléculaire:499.32

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

GSK4394835A Chemical Structure

CAS No.: 3032458-06-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

GSK4394835A is a reversible covalent inhibitor of PDE3B with a pIC₅₀ of 6.2. GSK4394835A can be used for cardiovascular disease research^[1].

IC₅₀ & Target^[1]

PDE3B

6.2 (pIC₅₀)

Voir tous les produits spécifiques à Isoform Phosphodiesterase (PDE) :

Chemical Information

CAS No. 3032458-06-0
Masse moléculaire 499.32
Formule C₂₇H₂₆BN₃O₆
SMILES

O=C(C1=CC(OC)=C2C=CC(OC)=CC2=N1)NC3=CC(C(N(CC4=CC=CC=C4)C)=O)=CC(B(O)O)=C3
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Samuel A. Eaton, et al. Covalent Binding of Boronic Acid-Based Inhibitor GSK4394835A to Phosphodiesterase 3B, a Drug Target for Cardiovascular Disease. bioRxiv. October 22, 2025.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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GSK4394835A

Voir tous les produits spécifiques à Isoform Phosphodiesterase (PDE)

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

GSK4394835A Related Classifications

HY-179595 Related Classifications