Riboflavin-13C5
Riboflavin-13C5 is the 13C-labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
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- Formule: C1313C4H15N4O6
- Masse moléculaire:375.29
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 83-88-5
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Masse moléculaire 375.29
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Formule C1313C4H15N4O6
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SMILES
O[13C@]([13C@](O)[13C@](O)[13C]O)CN1C(C=C(C)C(C)=C2)=C2N=C(C(N3)=O)C1=NC3=O
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Synonyms
Vitamin B2-13C5; E101-13C5
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Long, Q., et al., Riboflavin biosynthetic and regulatory factors as potential novel anti-infective drug targets. Chem Biol Drug Des, 2010. 75(4): p. 339-47. [Content Brief]
[3]. Zempleni, J., J.R. Galloway, and D.B. McCormick, Pharmacokinetics of orally and intravenously administered riboflavin in healthy humans. Am J Clin Nutr, 1996. 63(1): p. 54-66. [Content Brief]
[4]. Bertollo, C.M., et al., Characterization of the antinociceptive and anti-inflammatory activities of riboflavin in different experimental models. Eur J Pharmacol, 2006. 547(1-3): p. 184-91. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)