Salbutamol-d3
Based on 1 Customer Validation
Salbutamol-d3 (Albuterol-d3) is the deuterium labeled Salbutamol (HY-B1037). Salbutamol (Albuterol) is an orally active short-acting β2-adrenergic receptor agonist. Salbutamol promotes tumorigenesis in gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol can relax bronchial smooth muscle and is used to study bronchospasm induced by asthma and chronic obstructive pulmonary disease.
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- Pureté: 98.59%
- CAS No.: 1219798-60-3
- Formule: C13H18D3NO3
- Masse moléculaire:242.33
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Stockage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1219798-60-3
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Unlabeled Cas 18559-94-9
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Appearance Solid
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Masse moléculaire 242.33
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Formule C13H18D3NO3
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Color Off-white to light brown
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SMILES
OC([2H])([2H])C1=C(O)C=CC(C(CNC(C)(C)C)([2H])O)=C1
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Synonyms
Albuterol-d3; AH-3365-d3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 100 mg/mL (412.66 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (272 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Lu Y, et al. Chronic stress model simulated by salbutamol promotes tumorigenesis of gastric cancer cells through β2-AR/ERK/EMT pathway. J Cancer. 2022 Jan 1;13(2):401-412. [Content Brief]
[2]. Hong YP, et al. Effects of Castanospermine on Inflammatory Response in a Rat Model of Experimental Severe Acute Pancreatitis. Arch Med Res. 2016 Aug;47(6):436-445. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.1266 mL | 20.6330 mL | 41.2660 mL | 103.1651 mL |
| 5 mM | 0.8253 mL | 4.1266 mL | 8.2532 mL | 20.6330 mL | |
| 10 mM | 0.4127 mL | 2.0633 mL | 4.1266 mL | 10.3165 mL | |
| 15 mM | 0.2751 mL | 1.3755 mL | 2.7511 mL | 6.8777 mL | |
| 20 mM | 0.2063 mL | 1.0317 mL | 2.0633 mL | 5.1583 mL | |
| 25 mM | 0.1651 mL | 0.8253 mL | 1.6506 mL | 4.1266 mL | |
| 30 mM | 0.1376 mL | 0.6878 mL | 1.3755 mL | 3.4388 mL | |
| 40 mM | 0.1032 mL | 0.5158 mL | 1.0317 mL | 2.5791 mL | |
| 50 mM | 0.0825 mL | 0.4127 mL | 0.8253 mL | 2.0633 mL | |
| 60 mM | 0.0688 mL | 0.3439 mL | 0.6878 mL | 1.7194 mL | |
| 80 mM | 0.0516 mL | 0.2579 mL | 0.5158 mL | 1.2896 mL | |
| 100 mM | 0.0413 mL | 0.2063 mL | 0.4127 mL | 1.0317 mL |
Salbutamol-d3 Related Classifications
HY-B1037S Related Classifications
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