PKM2 activator 11
PKM2 activator 11 (Compound 23) is a PKM2 activator with an AC50 value of 92.12 nM. PKM2 activator 11 promotes PKM2 tetramerization and inhibits its nuclear translocation. PKM2 activator 11 suppresses glycolysis and the PKM2/STAT3 signaling pathway. PKM2 activator 11 induces Apoptosis. PKM2 activator 11 exhibits anti-CRC activity in vitro with potency and selectivity.
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- Formel: C27H23NO4S
- Molecular Weight:457.54
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
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STAT3 |
PKM2 |
Chemical Information
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Molecular Weight 457.54
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Formel C27H23NO4S
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SMILES
O=C(C1=O)C2=C(OC(CN3CCC(SC=C4)=C4C3)=C2C)C5=C1C6=C(C=C5)C(C)(C)C(C=C6)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
PKM2 activator 11 Related Classifications
HY-180795 Related Classifications
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