B7-H4
B7-H4 (also known as B7-S1, B7x and VCTN1), a member of the CD28/B7 family, is a transmembrane protein and a T-cell immune co-inhibitory molecule. B7-H4 negatively regulates T cell immune response and promotes immune escape by inhibiting the proliferation, cytokine secretion, and cell cycle of T cells. B7-H4 is limited expressed in normal peripheral tissues, whereas it is abnormally expressed in inflammation, autoimmune diseases and tumors, such as breast carcinomas. The amino acid sequence of human B7-H4 is highly conserved with approximately 87% amino acid identity to mouse.
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B7-H4 Recombinant Proteins (11)
- Species:
- Source:
- 1
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- 1
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
